| Factor |
ENTREZ.ID |
Probe |
Symbol |
Description |
Chromosome |
Chromosome Location |
GenBank |
Gene |
Cytoband |
UniGene |
PubMed |
Gene Ontology |
Pathway |
| 1 |
3535 |
31315_at |
IGL@ |
immunoglobulin lambda locus |
22 |
|
D84143 |
3535 |
22q11.1-q11.2 |
Hs.449585 |
14 |
|
|
| 1 |
|
31319_at |
|
|
|
|
M20707 |
|
|
|
|
|
|
| 1 |
10725 |
31364_i_at |
NFAT5 |
nuclear factor of activated T-cells 5, tonicity-responsive |
16 |
68156497 |
W27762 |
10725 |
16q22.1 |
Hs.371987 |
30 |
cytokine production regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter signal transduction excretion positive regulation of transcription from RNA polymerase II promoter nucleus cytoplasm transcription factor activity RNA polymerase II transcription factor activity protein binding |
Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway |
| 1 |
3021 |
31510_s_at |
H3F3B |
H3 histone, family 3B (H3.3B) |
17 |
-71284111 |
Z48950 |
3021 |
17q25 |
Hs.180877 |
21 |
nucleosome assembly chromosome organization and biogenesis (sensu Eukaryota) nucleosome nucleus chromosome DNA binding |
|
| 1 |
57142 |
31536_at |
RTN4 |
reticulon 4 |
2 |
-55052832 |
AB020693 |
57142 |
2p16.3 |
Hs.645283 |
54 |
negative regulation of anti-apoptosis negative regulation of axon extension regulation of apoptosis nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane integral to membrane integral to endoplasmic reticulum membrane protein binding |
|
| 1 |
3304 |
31692_at |
HSPA1B |
heat shock 70kDa protein 1B |
6 |
3043121 |
M59830 |
3304 |
6p21.3 |
Hs.274402 |
50 |
mRNA catabolic process protein folding anti-apoptosis response to unfolded protein nucleus cytoplasm mitochondrion endoplasmic reticulum nucleotide binding ATP binding unfolded protein binding |
|
| 1 |
10095 |
34095_f_at |
ARPC1B |
actin related protein 2/3 complex, subunit 1B, 41kDa |
7 |
98810264 |
U80114 |
10095 |
7q22.1 |
Hs.449574 Hs.489284 Hs.503878 Hs.533963 |
23 |
cell motility cell adhesion Arp2/3 protein complex membrane structural constituent of cytoskeleton protein binding |
Regulation of actin cytoskeleton |
| 1 |
3576 |
35566_f_at |
IL8 |
interleukin 8 |
4 |
74825138 |
AF015128 |
3576 |
4q13-q21 |
Hs.624 Hs.449585 Hs.551925 Hs.561078 Hs.654584 |
480 |
angiogenesis cell motility chemotaxis inflammatory response immune response cell cycle arrest G-protein coupled receptor protein signaling pathway intracellular signaling cascade cell-cell signaling negative regulation of cell proliferation calcium-mediated signaling regulation of cell adhesion neutrophil chemotaxis neutrophil activation regulation of retroviral genome replication induction of positive chemotaxis extracellular region extracellular space interleukin-8 receptor binding protein binding chemokine activity |
Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway Epithelial cell signaling in Helicobacter pylori infection Bladder cancer |
| 1 |
8341 |
36347_f_at |
HIST1H2BN |
histone cluster 1, H2bn |
6 |
27914418 |
Z98744 |
8341 |
6p22-p21.3 |
Hs.673851 |
18 |
nucleosome assembly chromosome organization and biogenesis (sensu Eukaryota) nucleosome nucleus chromosome DNA binding |
|
| 1 |
10859 |
35926_s_at |
LILRB1 |
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
19 |
59833779, 59833719, 59820440 |
AF009005 |
10859 |
19q13.4 |
Hs.655593 Hs.667388 |
37 |
immune response response to virus membrane integral to membrane receptor activity protein phosphatase 1 binding |
|
| 1 |
3119 |
36773_f_at |
HLA-DQB1 |
major histocompatibility complex, class II, DQ beta 1 |
6 |
-32735634 |
M81141 |
3119 |
6p21.3 |
Hs.409934 Hs.534322 Hs.653339 |
161 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune response immune response cell cycle membrane membrane integral to membrane MHC class II protein complex GTP binding MHC class II receptor activity |
Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus |
| 1 |
7168 |
36790_at |
TPM1 |
tropomyosin 1 (alpha) |
15 |
61121890, 61127688 |
M19267 |
7168 |
15q22.1 |
Hs.133892 |
60 |
cell motility regulation of muscle contraction regulation of heart contraction cytoplasm cytoskeleton muscle thin filament tropomyosin actin binding structural constituent of cytoskeleton structural constituent of muscle |
|
| 1 |
7168 |
36791_g_at |
TPM1 |
tropomyosin 1 (alpha) |
15 |
61121890, 61127688 |
M19267 |
7168 |
15q22.1 |
Hs.133892 |
60 |
cell motility regulation of muscle contraction regulation of heart contraction cytoplasm cytoskeleton muscle thin filament tropomyosin actin binding structural constituent of cytoskeleton structural constituent of muscle |
|
| 1 |
7168 |
36792_at |
TPM1 |
tropomyosin 1 (alpha) |
15 |
61121890, 61127688 |
Z24727 |
7168 |
15q22.1 |
Hs.133892 |
60 |
cell motility regulation of muscle contraction regulation of heart contraction cytoplasm cytoskeleton muscle thin filament tropomyosin actin binding structural constituent of cytoskeleton structural constituent of muscle |
|
| 1 |
9744 |
37411_at |
CENTB1 |
centaurin, beta 1 |
17 |
7180596 |
D30758 |
9744 |
17p13.1 |
Hs.337242 |
10 |
intracellular signaling cascade regulation of GTPase activity phospholipase C activity GTPase activator activity zinc ion binding metal ion binding |
|
| 1 |
3134 |
37420_i_at |
HLA-F |
major histocompatibility complex, class I, F |
6 |
945922, 1143812, 29799095 |
X17093 |
3134 |
6p21.3 |
Hs.519972 |
51 |
antigen processing and presentation of peptide antigen via MHC class I immune response antigen processing and presentation membrane integral to membrane MHC class I protein complex MHC class I receptor activity |
Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus |
| 1 |
3495 |
37467_at |
IGHD |
immunoglobulin heavy constant delta |
14 |
|
K02882 |
3495 |
14q32.33 |
Hs.510635 |
17 |
immune response antigen binding |
|
| 1 |
3625 |
38545_at |
INHBB |
inhibin, beta B |
2 |
120820188 |
M31682 |
3625 |
2cen-q13 |
Hs.1735 |
46 |
ovarian follicle development defense response response to external stimulus cell differentiation growth positive regulation of follicle-stimulating hormone secretion negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor biosynthetic process extracellular region cytokine activity hormone activity growth factor activity protein homodimerization activity host cell surface receptor binding |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
| 1 |
3212 |
39610_at |
HOXB2 |
homeobox B2 |
17 |
-43975019 |
X16665 |
3212 |
17q21-q22 |
Hs.514289 |
21 |
regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent multicellular organismal development multicellular organismal development circulation nucleus nucleus transcription factor activity transcription factor activity sequence-specific DNA binding |
|
| 1 |
1230 |
39994_at |
CCR1 |
chemokine (C-C motif) receptor 1 |
3 |
-46218203 |
D10925 |
1230 |
3p21 |
Hs.301921 |
58 |
chemotaxis inflammatory response immune response cell adhesion G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration cell-cell signaling cytokine and chemokine mediated signaling pathway plasma membrane plasma membrane integral to plasma membrane rhodopsin-like receptor activity receptor activity protein binding C-C chemokine receptor activity |
Cytokine-cytokine receptor interaction |
| 1 |
4050 |
40729_s_at |
LTB |
lymphotoxin beta (TNF superfamily, member 3) |
6 |
-31656316, -2994460, -2795924 |
Y14768 |
4050 |
6p21.3 |
Hs.376208 |
31 |
immune response signal transduction cell-cell signaling cellular_component extracellular space membrane integral to membrane cytokine activity tumor necrosis factor receptor binding |
Cytokine-cytokine receptor interaction |
| 1 |
914 |
40738_at |
CD2 |
CD2 molecule |
1 |
117098608 |
M16336 |
914 |
1p13 |
Hs.523500 |
65 |
lipid raft polarization induction of apoptosis cell surface receptor linked signal transduction cell-cell adhesion natural killer cell activation positive regulation of myeloid dendritic cell activation T cell activation regulation of T cell differentiation integral to plasma membrane membrane receptor activity protein binding protein binding |
Cell adhesion molecules (CAMs) Hematopoietic cell lineage |
| 1 |
22856 |
41447_at |
CHSY1 |
carbohydrate (chondroitin) synthase 1 |
15 |
-99533455 |
AB023207 |
22856 |
15q26.3 |
Hs.110488 |
8 |
membrane integral to membrane transferase activity metal ion binding glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
Chondroitin sulfate biosynthesis Glycan structures - biosynthesis 1 |
| 1 |
3109 |
41609_at |
HLA-DMB |
major histocompatibility complex, class II, DM beta |
6 |
-33010393, -4088489 |
U15085 |
3109 |
6p21.3 |
Hs.654428 |
46 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune response lysosome endosome membrane integral to membrane MHC class II protein complex |
Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus |
| 1 |
9620 |
41660_at |
CELSR1 |
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) |
22 |
-45135394 |
AL031588 |
9620 |
22q13.3 |
Hs.252387 |
11 |
neural tube closure homophilic cell adhesion signal transduction neuropeptide signaling pathway multicellular organismal development central nervous system development central nervous system development locomotory behavior establishment of polarity of embryonic epithelium inner ear morphogenesis apical protein localization integral to plasma membrane membrane G-protein coupled receptor activity calcium ion binding protein dimerization activity |
|
| 1 |
3059 |
31820_at |
HCLS1 |
hematopoietic cell-specific Lyn substrate 1 |
3 |
-122832936 |
X16663 |
3059 |
3q13 |
Hs.14601 |
30 |
regulation of transcription, DNA-dependent intracellular signaling cascade positive regulation of cell proliferation response to hormone stimulus erythrocyte differentiation positive regulation of tyrosine phosphorylation of STAT protein nucleus DNA-directed RNA polymerase II, core complex cytoplasm mitochondrion membrane transcription factor activity protein binding SH3 domain binding |
Tight junction Pathogenic Escherichia coli infection - EHEC Pathogenic Escherichia coli infection - EPEC |
| 1 |
951 |
31870_at |
CD37 |
CD37 molecule |
19 |
54530488 |
X14046 |
951 |
19q13.3 |
Hs.166556 |
16 |
protein amino acid N-linked glycosylation plasma membrane integral to plasma membrane membrane integral to membrane |
Hematopoietic cell lineage |
| 1 |
7764 |
32034_at |
ZNF217 |
zinc finger protein 217 |
20 |
-51617018 |
AF041259 |
7764 |
20q13.2 |
Hs.155040 |
13 |
regulation of transcription, DNA-dependent intracellular transcription factor activity zinc ion binding metal ion binding |
|
| 1 |
5790 |
32070_at |
PTPRCAP |
protein tyrosine phosphatase, receptor type, C-associated protein |
11 |
-66959556 |
X97267 |
5790 |
11q13.3 |
Hs.155975 |
10 |
defense response plasma membrane integral to plasma membrane |
|
| 1 |
|
32119_at |
|
|
|
|
AL049423 |
|
|
|
|
|
|
| 1 |
5880 |
32736_at |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
22 |
-35951257 |
W68830 |
5880 |
22q13.1 |
Hs.517601 |
44 |
chemotaxis signal transduction small GTPase mediated signal transduction cell projection biogenesis actin cytoskeleton organization and biogenesis intracellular membrane fraction nuclear envelope cytoplasm nucleotide binding GTPase activity protein binding GTP binding |
MAPK signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Leukocyte transendothelial migration Regulation of actin cytoskeleton Colorectal cancer Pancreatic cancer |
| 1 |
23032 |
33219_at |
USP33 |
ubiquitin specific peptidase 33 |
1 |
-77934263, -77949927 |
AB029020 |
23032 |
1p31.1 |
Hs.480597 |
11 |
ubiquitin-dependent protein catabolic process protein deubiquitination protein deubiquitination cytoplasm VCB complex ubiquitin thiolesterase activity protein binding protein binding cysteine-type peptidase activity zinc ion binding metal ion binding |
|
| 1 |
9052 |
33730_at |
GPRC5A |
G protein-coupled receptor, family C, group 5, member A |
12 |
12935222 |
AF095448 |
9052 |
12p13-p12.3 |
Hs.631733 |
12 |
signal transduction G-protein coupled receptor protein signaling pathway integral to plasma membrane membrane cytoplasmic vesicle receptor activity metabotropic glutamate, GABA-B-like receptor activity |
|
| 1 |
220594 |
34677_f_at |
LOC220594 |
TL132 protein |
17 |
|
AJ012755 |
220594 |
17p11.2 |
Hs.234573 Hs.462475 |
2 |
ubiquitin-dependent protein catabolic process ubiquitin thiolesterase activity |
|
| 1 |
26509 |
34678_at |
FER1L3 |
fer-1-like 3, myoferlin (C. elegans) |
10 |
-95056175 |
AL096713 |
26509 |
10q24 |
Hs.655278 |
11 |
muscle contraction circulation nuclear envelope plasma membrane integral to membrane |
|
| 1 |
7779 |
34759_at |
SLC30A1 |
solute carrier family 30 (zinc transporter), member 1 |
1 |
-209815005 |
U68494 |
7779 |
1q32-q41 |
Hs.519469 |
4 |
in utero embryonic development cation transport zinc ion transport cellular zinc ion homeostasis nutrient import membrane integral to membrane zinc ion binding cation transmembrane transporter activity |
|
| 1 |
1307 |
35168_f_at |
COL16A1 |
collagen, type XVI, alpha 1 |
1 |
-31890434 |
M92642 |
1307 |
1p35-p34 |
Hs.368921 |
10 |
phosphate transport cell adhesion integrin-mediated signaling pathway female pregnancy proteinaceous extracellular matrix collagen type XVI cytoplasm integrin binding structural molecule activity protein binding |
|
| 1 |
6337 |
35207_at |
SCNN1A |
sodium channel, nonvoltage-gated 1 alpha |
12 |
-6326275 |
X76180 |
6337 |
12p13 |
Hs.591047 |
42 |
ion transport sodium ion transport excretion response to stimulus membrane fraction integral to plasma membrane membrane ion channel activity protein binding amiloride-sensitive sodium channel activity sodium ion binding |
Taste transduction |
| 1 |
7358 |
35214_at |
UGDH |
UDP-glucose dehydrogenase |
4 |
-39176770 |
AF061016 |
7358 |
4p15.1 |
Hs.572518 |
17 |
UDP-glucose metabolic process glycosaminoglycan biosynthetic process UDP-glucuronate biosynthetic process electron transport gastrulation (sensu Mammalia) UDP-glucose 6-dehydrogenase activity electron carrier activity NAD binding |
Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Starch and sucrose metabolism Nucleotide sugars metabolism |
| 1 |
7188 |
35238_at |
TRAF5 |
TNF receptor-associated factor 5 |
1 |
209566579, 209586328, 209566801 |
AB000509 |
7188 |
1q32 |
Hs.523930 |
44 |
signal transduction regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade cytoplasm signal transducer activity protein binding protein binding zinc ion binding metal ion binding |
Small cell lung cancer |
| 1 |
6049 |
35656_at |
RNF6 |
ring finger protein (C3H2C3 type) 6 |
13 |
-25684905, -25684904 |
AJ010346 |
6049 |
13q12.2 |
Hs.136885 |
6 |
ubiquitin-dependent protein catabolic process biological_process negative regulation of axon extension positive regulation of transcription, DNA-dependent cellular_component cytoplasm PML body axon DNA binding ubiquitin-protein ligase activity protein binding zinc ion binding transcription activator activity metal ion binding |
|
| 1 |
4046 |
36493_at |
LSP1 |
lymphocyte-specific protein 1 |
11 |
1846478, 1848674, 1848729, 1830775 |
M33552 |
4046 |
11p15.5 |
Hs.56729 |
23 |
cell motility cellular defense response signal transduction actin cytoskeleton membrane actin binding signal transducer activity |
|
| 1 |
1952 |
36499_at |
CELSR2 |
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) |
1 |
109594163 |
D87469 |
1952 |
1p21 |
Hs.57652 |
6 |
homophilic cell adhesion signal transduction neuropeptide signaling pathway multicellular organismal development membrane integral to membrane receptor activity G-protein coupled receptor activity G-protein coupled receptor activity calcium ion binding |
|
| 1 |
54453 |
36550_at |
RIN2 |
Ras and Rab interactor 2 |
20 |
19818209 |
AL049538 |
54453 |
20p11.22 |
Hs.472270 |
7 |
endocytosis small GTPase mediated signal transduction cellular_component cytoplasm small GTPase regulator activity GTPase activator activity Rab guanyl-nucleotide exchange factor activity |
|
| 1 |
64746 |
36827_at |
ACBD3 |
acyl-Coenzyme A binding domain containing 3 |
1 |
-224399004 |
AF020762 |
64746 |
1q42.12 |
Hs.520207 |
10 |
steroid biosynthetic process transport mitochondrion membrane integral to membrane acyl-CoA binding binding |
|
| 1 |
5493 |
36890_at |
PPL |
periplakin |
16 |
-4872508 |
AF001691 |
5493 |
16p13.3 |
Hs.192233 |
24 |
keratinization cytoplasm mitochondrion cytoskeleton cell junction structural constituent of cytoskeleton protein binding |
|
| 1 |
7465 |
36909_at |
WEE1 |
WEE1 homolog (S. pombe) |
11 |
9550915 |
X62048 |
7465 |
11p15.3-p15.1 |
Hs.249441 |
48 |
regulation of progression through cell cycle protein amino acid phosphorylation cell cycle mitosis cell division nucleus nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein-tyrosine kinase activity protein binding ATP binding transferase activity |
Cell cycle |
| 1 |
79068 |
37242_at |
FTO |
fat mass and obesity associated |
16 |
52295375 |
U79260 |
79068 |
16q12.2 |
Hs.528833 |
9 |
determination of left/right symmetry embryonic limb morphogenesis |
|
| 1 |
7033 |
37897_s_at |
TFF3 |
trefoil factor 3 (intestinal) |
21 |
-42605232 |
AI985964 |
7033 |
21q22.3 |
Hs.82961 |
39 |
defense response digestion extracellular region secretory granule |
|
| 1 |
8799 |
37900_at |
PEX11B |
peroxisomal biogenesis factor 11B |
1 |
144227739 |
AF093670 |
8799 |
1q21.1 |
Hs.504284 |
10 |
peroxisome fission mitochondrion peroxisome peroxisomal membrane integral to peroxisomal membrane membrane integral to membrane protein binding |
|
| 1 |
382 |
37984_s_at |
ARF6 |
ADP-ribosylation factor 6 |
14 |
49429485 |
M57763 |
382 |
14q21.3 |
Hs.525330 Hs.593068 Hs.694988 |
67 |
ER to Golgi vesicle-mediated transport cell motility cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization and biogenesis ruffle organization and biogenesis regulation of Rac protein signal transduction negative regulation of receptor mediated endocytosis ruffle intracellular membrane fraction cytoplasm endosome plasma membrane cell cortex nucleotide binding GTPase activity protein binding GTP binding |
Cholera - Infection |
| 1 |
5698 |
38287_at |
PSMB9 |
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) |
6 |
32929915, 4202792, 4007991 |
AA808961 |
5698 |
6p21.3 |
Hs.654585 |
50 |
proteolysis ubiquitin-dependent protein catabolic process immune response antigen processing and presentation cytoplasm cytosol proteasome core complex (sensu Eukaryota) threonine endopeptidase activity |
|
| 1 |
9338 |
38317_at |
TCEAL1 |
transcription elongation factor A (SII)-like 1 |
X |
102770547, 102770303 |
M99701 |
9338 |
Xq22.1 |
Hs.95243 |
10 |
negative regulation of transcription from RNA polymerase II promoter transcription regulation of transcription, DNA-dependent nucleus transcription factor activity RNA polymerase II transcription factor activity |
|
| 1 |
51599 |
38324_at |
LSR |
lipolysis stimulated lipoprotein receptor |
19 |
40431398 |
AD000684 |
51599 |
19q13.12 |
Hs.466507 |
8 |
liver development embryonic development plasma membrane integral to membrane chylomicron receptor activity lipid transporter activity |
|
| 1 |
3488 |
38650_at |
IGFBP5 |
insulin-like growth factor binding protein 5 |
2 |
-217245073 |
L27560 |
3488 |
2q33-q36 |
Hs.635441 |
66 |
regulation of cell growth signal transduction extracellular region endoplasmic reticulum insulin-like growth factor binding |
|
| 1 |
5376 |
38653_at |
PMP22 |
peripheral myelin protein 22 |
17 |
-15073821 |
D11428 |
5376 |
17p12-p11.2 |
Hs.372031 |
91 |
synaptic transmission peripheral nervous system development sensory perception of sound mechanosensory behavior negative regulation of cell proliferation integral to plasma membrane membrane |
|
| 1 |
11151 |
38976_at |
CORO1A |
coronin, actin binding protein, 1A |
16 |
30102426 |
D44497 |
11151 |
16p11.2 |
Hs.415067 |
17 |
transport cell motility mitosis cytoplasm lysosomal membrane actin cytoskeleton membrane cytoplasmic vesicle actin binding structural molecule activity protein binding |
|
| 1 |
26268 |
38990_at |
FBXO9 |
F-box protein 9 |
6 |
53043729, 53037754, 53038215 |
AL031178 |
26268 |
6p12.3-p11.2 |
Hs.216653 |
9 |
protein ubiquitination ubiquitin ligase complex ubiquitin-protein ligase activity |
|
| 1 |
2029 |
39012_g_at |
ENSA |
endosulfine alpha |
1 |
-148866147, -148861224, -148862378 |
X99906 |
2029 |
1q21.2 |
Hs.632456 |
13 |
transport response to nutrient cytoplasm receptor binding ion channel inhibitor activity |
|
| 1 |
8848 |
39032_at |
TSC22D1 |
TSC22 domain family, member 1 |
13 |
-43905660 |
AJ222700 |
8848 |
13q14 |
Hs.507916 |
17 |
transcription regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter cytoplasm transcription factor activity |
|
| 1 |
9528 |
39033_at |
TMEM59 |
transmembrane protein 59 |
1 |
-54269938 |
Z78368 |
9528 |
1p36-p31 |
Hs.523262 |
10 |
membrane integral to membrane |
|
| 1 |
7267 |
39065_s_at |
TTC3 |
tetratricopeptide repeat domain 3 |
21 |
37377116, 37367440 |
D83327 |
7267 |
21q22.2 |
Hs.368214 |
9 |
biological_process cellular_component binding protein binding zinc ion binding metal ion binding |
|
| 1 |
7280 |
39331_at |
TUBB2A |
tubulin, beta 2A |
6 |
-3098902 |
X79535 |
7280 |
6p25 |
Hs.654543 |
71 |
microtubule-based movement protein polymerization cytoplasm cytoskeleton microtubule protein complex nucleotide binding GTPase activity structural constituent of cytoskeleton protein binding GTP binding |
Gap junction Pathogenic Escherichia coli infection - EHEC Pathogenic Escherichia coli infection - EPEC |
| 1 |
966 |
39351_at |
CD59 |
CD59 molecule, complement regulatory protein |
11 |
-33681133 |
M84349 |
966 |
11p13 |
Hs.278573 Hs.653685 Hs.693685 |
80 |
defense response immune response cell surface receptor linked signal transduction blood coagulation membrane fraction plasma membrane protein binding GPI anchor binding |
Complement and coagulation cascades Hematopoietic cell lineage |
| 1 |
928 |
39389_at |
CD9 |
CD9 molecule |
12 |
6179815 |
M38690 |
928 |
12p13.3 |
Hs.114286 |
73 |
cell motility cell adhesion fusion of sperm to egg plasma membrane platelet activation paranodal junction assembly plasma membrane integral to plasma membrane membrane integral to membrane protein binding |
Hematopoietic cell lineage |
| 1 |
10434 |
39396_at |
LYPLA1 |
lysophospholipase I |
8 |
-55121491 |
AF081281 |
10434 |
8q11.23 |
Hs.435850 |
11 |
lipid metabolic process fatty acid metabolic process membrane fraction cytoplasm lysophospholipase activity hydrolase activity |
Glycerophospholipid metabolism |
| 1 |
7026 |
39397_at |
NR2F2 |
nuclear receptor subfamily 2, group F, member 2 |
15 |
94674949 |
M64497 |
7026 |
15q26 |
Hs.347991 |
19 |
transcription regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction nucleus nucleus transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity zinc ion binding sequence-specific DNA binding metal ion binding |
|
| 1 |
665 |
39436_at |
BNIP3L |
BCL2/adenovirus E1B 19kDa interacting protein 3-like |
8 |
26296439 |
AF079221 |
665 |
8p21 |
Hs.131226 |
15 |
apoptosis induction of apoptosis negative regulation of survival gene product activity positive regulation of apoptosis negative regulation of apoptosis defense response to virus nuclear envelope mitochondrion mitochondrial envelope endoplasmic reticulum membrane integral to membrane lamin binding protein homodimerization activity protein heterodimerization activity |
|
| 1 |
25814 |
39685_at |
ATXN10 |
ataxin 10 |
22 |
44446350 |
AL050282 |
25814 |
22q13.31 |
Hs.475125 |
17 |
biological_process cell death cellular_component cytoplasm binding protein binding |
|
| 1 |
6451 |
39714_at |
SH3BGRL |
SH3 domain binding glutamic acid-rich protein like |
X |
80344277 |
AF042081 |
6451 |
Xq13.3 |
Hs.108029 |
10 |
nucleus cytoplasm SH3/SH2 adaptor activity |
|
| 1 |
1654 |
39744_at |
DDX3X |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked |
X |
41077594 |
AF000982 |
1654 |
Xp11.3-p11.23 |
Hs.380774 |
23 |
nucleus cytoplasm nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity ATP binding hydrolase activity |
|
| 1 |
3693 |
39754_at |
ITGB5 |
integrin, beta 5 |
3 |
-125964485 |
X53002 |
3693 |
3q21.2 |
Hs.536663 |
46 |
cell adhesion cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development integrin complex membrane integral to membrane receptor activity integrin binding protein binding |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton |
| 1 |
7494 |
39756_g_at |
XBP1 |
X-box binding protein 1 |
22 |
-27520548 |
Z93930 |
7494 |
22q12.1 22q12 |
Hs.437638 |
42 |
transcription regulation of transcription, DNA-dependent immune response nucleus transcription factor activity sequence-specific DNA binding protein dimerization activity |
|
| 1 |
10241 |
40063_at |
CALCOCO2 |
calcium binding and coiled-coil domain 2 |
17 |
44263370 |
U22897 |
10241 |
17q21.32 |
Hs.514920 |
10 |
viral reproduction nucleus cytoplasm protein binding |
|
| 1 |
11098 |
40078_at |
PRSS23 |
protease, serine, 23 |
11 |
86189138 |
AF015287 |
11098 |
11q14.1 |
Hs.25338 Hs.694882 |
13 |
proteolysis nucleus serine-type endopeptidase activity peptidase activity |
|
| 1 |
|
40079_at |
|
|
|
|
AA156240 |
|
|
|
|
|
|
| 1 |
604 |
40091_at |
BCL6 |
B-cell CLL/lymphoma 6 (zinc finger protein 51) |
3 |
-188921858 |
U00115 |
604 |
3q27 |
Hs.478588 |
95 |
protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter cell morphogenesis negative regulation of cell-matrix adhesion regulation of germinal center formation negative regulation of T-helper 2 type immune response negative regulation of B cell apoptosis transcription regulation of transcription, DNA-dependent response to DNA damage stimulus Rho protein signal transduction spermatogenesis protein localization negative regulation of cell proliferation actin cytoskeleton organization and biogenesis B cell differentiation negative regulation of cell growth positive regulation of B cell proliferation regulation of Rho GTPase activity negative regulation of mast cell cytokine production negative regulation of Rho protein signal transduction T-helper 2 type immune response positive regulation of apoptosis regulation of memory T cell differentiation negative regulation of cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of S phase of mitotic cell cycle negative regulation of isotype switching to IgE isotypes erythrocyte development regulation of inflammatory response regulation of immune response positive regulation of cell motility intracellular nucleus nucleus replication fork DNA binding chromatin binding protein binding zinc ion binding transcription repressor activity transcription repressor activity sequence-specific DNA binding metal ion binding |
|
| 1 |
5908 |
40146_at |
RAP1B |
RAP1B, member of RAS oncogene family |
12 |
67290918 |
AL080212 |
5908 |
12q14 |
Hs.369920 |
28 |
small GTPase mediated signal transduction intracellular cytoplasm membrane nucleotide binding GTP binding |
MAPK signaling pathway Focal adhesion Leukocyte transendothelial migration Long-term potentiation Renal cell carcinoma |
| 1 |
5830 |
40152_r_at |
PEX5 |
peroxisomal biogenesis factor 5 |
12 |
7234223 |
Z48054 |
5830 |
12p13.3 |
Hs.567327 |
39 |
protein transport cytoplasm peroxisome peroxisomal membrane membrane peroxisome matrix targeting signal-1 binding protein binding |
|
| 1 |
3485 |
40422_at |
IGFBP2 |
insulin-like growth factor binding protein 2, 36kDa |
2 |
217206371 |
X16302 |
3485 |
2q33-q34 |
Hs.438102 |
65 |
regulation of cell growth extracellular region extracellular space insulin-like growth factor binding |
|
| 1 |
10641 |
40499_r_at |
TUSC4 |
tumor suppressor candidate 4 |
3 |
-50359922 |
AF040708 |
10641 |
3p21.3 |
Hs.437083 |
8 |
cell cycle negative regulation of progression through cell cycle protein binding |
|
| 1 |
5788 |
40518_at |
PTPRC |
protein tyrosine phosphatase, receptor type, C |
1 |
196874759 |
Y00062 |
5788 |
1q31-q32 |
Hs.654514 |
131 |
negative regulation of T cell mediated cytotoxicity negative regulation of cytokine and chemokine mediated signaling pathway negative regulation of protein kinase activity negative regulation of protein kinase activity protein amino acid dephosphorylation protein amino acid dephosphorylation cell surface receptor linked signal transduction T cell differentiation B cell proliferation positive regulation of T cell proliferation positive regulation of protein kinase activity T cell receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway positive regulation of antigen receptor-mediated signaling pathway release of sequestered calcium ion into cytosol defense response to virus regulation of cell cycle integral to plasma membrane focal adhesion membrane protein tyrosine phosphatase activity protein tyrosine phosphatase activity receptor activity transmembrane receptor protein tyrosine phosphatase activity hydrolase activity phosphoric monoester hydrolase activity protein kinase binding protein kinase binding |
Cell adhesion molecules (CAMs) T cell receptor signaling pathway |
| 1 |
2752 |
40522_at |
GLUL |
glutamate-ammonia ligase (glutamine synthetase) |
1 |
-180618291 |
X59834 |
2752 |
1q31 |
Hs.518525 |
25 |
regulation of neurotransmitter levels glutamine biosynthetic process nitrogen compound metabolic process cytoplasm glutamate-ammonia ligase activity ligase activity |
Glutamate metabolism Peptidoglycan biosynthesis Nitrogen metabolism |
| 1 |
1488 |
40780_at |
CTBP2 |
C-terminal binding protein 2 |
10 |
-126666407 |
AF016507 |
1488 |
10q26.13 |
Hs.501345 |
21 |
metabolic process negative regulation of cell proliferation viral genome replication oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor cofactor binding NAD binding |
Wnt signaling pathway Notch signaling pathway Chronic myeloid leukemia |
| 1 |
147179 |
40787_at |
WIPF2 |
WAS/WASL interacting protein family, member 2 |
17 |
35629099 |
U90911 |
147179 |
17q21.2 |
Hs.421622 Hs.694045 |
11 |
cytoplasm cytoskeleton actin binding |
|
| 1 |
8553 |
40790_at |
BHLHB2 |
basic helix-loop-helix domain containing, class B, 2 |
3 |
4996207 |
AB004066 |
8553 |
3p26 |
Hs.171825 |
21 |
negative regulation of transcription, DNA-dependent nucleus transcription factor activity protein binding transcription repressor activity |
Circadian rhythm |
| 1 |
26092 |
40832_s_at |
TOR1AIP1 |
torsin A interacting protein 1 |
1 |
178118042 |
AL050126 |
26092 |
1q24.2 |
Hs.496459 |
10 |
membrane integral to membrane |
|
| 1 |
351 |
41136_s_at |
APP |
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) |
21 |
-26174732 |
X13466 |
351 |
21q21.2 21q21.3 |
Hs.434980 |
561 |
cellular copper ion homeostasis endocytosis apoptosis cell adhesion Notch signaling pathway neuromuscular process extracellular region integral to plasma membrane cell surface membrane serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity iron ion binding copper ion binding heparin binding zinc ion binding identical protein binding metal ion binding |
Neurodegenerative Disorders Alzheimer's disease |
| 1 |
1495 |
41155_at |
CTNNA1 |
catenin (cadherin-associated protein), alpha 1, 102kDa |
5 |
138117005 |
U03100 |
1495 |
5q31 |
Hs.534797 |
44 |
cell adhesion apical junction assembly cytoplasm actin cytoskeleton cell junction structural molecule activity protein binding vinculin binding cadherin binding |
Adherens junction Tight junction Leukocyte transendothelial migration Endometrial cancer |
| 1 |
3507 |
41164_at |
IGHM |
immunoglobulin heavy constant mu |
14 |
|
X67301 |
3507 |
14q32.33 |
Hs.510635 |
24 |
activation of MAPK activity immune response biological_process immunoglobulin mediated immune response antigen processing and presentation positive regulation of B cell proliferation early endosome to late endosome transport positive regulation of endocytosis positive regulation of peptidyl-tyrosine phosphorylation B cell receptor signaling pathway membrane fraction external side of plasma membrane membrane B cell receptor complex immunoglobulin complex, circulating perinuclear region of cytoplasm antigen binding antigen binding receptor activity transmembrane receptor activity protein binding |
|
| 1 |
3507 |
41165_g_at |
IGHM |
immunoglobulin heavy constant mu |
14 |
|
X67301 |
3507 |
14q32.33 |
Hs.510635 |
24 |
activation of MAPK activity immune response biological_process immunoglobulin mediated immune response antigen processing and presentation positive regulation of B cell proliferation early endosome to late endosome transport positive regulation of endocytosis positive regulation of peptidyl-tyrosine phosphorylation B cell receptor signaling pathway membrane fraction external side of plasma membrane membrane B cell receptor complex immunoglobulin complex, circulating perinuclear region of cytoplasm antigen binding antigen binding receptor activity transmembrane receptor activity protein binding |
|
| 1 |
23022 |
41191_at |
PALLD |
palladin, cytoskeletal associated protein |
4 |
169654791 |
AB023209 |
23022 |
4q32.3 |
Hs.151220 |
18 |
protein amino acid phosphorylation cytoskeleton organization and biogenesis nucleus actin filament vascular endothelial growth factor receptor activity protein binding ATP binding muscle alpha-actinin binding |
|
| 1 |
10049 |
41233_at |
DNAJB6 |
DnaJ (Hsp40) homolog, subfamily B, member 6 |
7 |
156822471, 156822470 |
AB014888 |
10049 |
7q36.3 |
Hs.490745 |
21 |
protein folding response to unfolded protein negative regulation of caspase activity intermediate filament organization nucleus cytoplasm perinuclear region of cytoplasm ATPase activator activity heat shock protein binding chaperone binding |
|
| 1 |
3127 |
41723_s_at |
HLA-DRB5 |
major histocompatibility complex, class II, DR beta 5 |
6 |
-32593138 |
M32578 |
3127 |
6p21.3 |
Hs.534322 |
63 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune response integral to plasma membrane membrane integral to membrane MHC class II protein complex MHC class II receptor activity |
Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage Type I diabetes mellitus |
| 1 |
341 |
41764_at |
APOC1 |
apolipoprotein C-I |
19 |
50109760 |
AA976838 |
341 |
19q13.2 |
Hs.110675 |
43 |
lipid metabolic process lipid transport lipoprotein metabolic process extracellular region endoplasmic reticulum lipid transporter activity |
|
| 1 |
10160 |
32148_at |
FARP1 |
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
13 |
97593434 |
AI701049 |
10160 |
13q32.2 |
Hs.403917 |
9 |
regulation of Rho protein signal transduction intracellular cytoplasm cytoskeleton extrinsic to membrane guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity binding cytoskeletal protein binding |
|
| 1 |
9415 |
32190_at |
FADS2 |
fatty acid desaturase 2 |
11 |
61352288 |
AL050118 |
9415 |
11q12-q13.1 |
Hs.502745 |
15 |
lipid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process membrane fraction integral to plasma membrane membrane iron ion binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water heme binding |
Linoleic acid metabolism PPAR signaling pathway |
| 1 |
79921 |
32251_at |
TCEAL4 |
transcription elongation factor A (SII)-like 4 |
X |
102727074 |
AA149307 |
79921 |
Xq22.2 |
Hs.194329 |
10 |
transcription regulation of transcription, DNA-dependent |
|
| 1 |
3117 |
32773_at |
HLA-DQA1 |
major histocompatibility complex, class II, DQ alpha 1 |
6 |
32713160 |
AA868382 |
3117 |
6p21.3 |
Hs.387679 |
89 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune response immune response antigen processing and presentation integral to plasma membrane membrane integral to membrane MHC class II protein complex MHC class II receptor activity MHC class II receptor activity |
Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus |
| 1 |
2065 |
32787_at |
ERBB3 |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
12 |
54760158 |
M34309 |
2065 |
12q13 |
Hs.118681 |
85 |
protein amino acid phosphorylation protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway peripheral nervous system development heart development integral to plasma membrane membrane apical plasma membrane lateral plasma membrane nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity epidermal growth factor receptor activity protein binding ATP binding transferase activity protein heterodimerization activity |
ErbB signaling pathway Calcium signaling pathway |
| 1 |
28639 |
32794_g_at |
TRBC1 |
T cell receptor beta constant 1 |
7 |
|
X00437 |
28639 |
7q34 |
Hs.654496 |
5 |
immune response membrane receptor activity protein binding |
|
| 1 |
3895 |
32846_s_at |
KTN1 |
kinectin 1 (kinesin receptor) |
14 |
55116677 |
D13629 |
3895 |
14q22.1 |
Hs.509414 |
26 |
microtubule-based movement membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane membrane molecular_function receptor activity |
|
| 1 |
6772 |
33338_at |
STAT1 |
signal transducer and activator of transcription 1, 91kDa |
2 |
-191548509, -191542121 |
M97936 |
6772 |
2q32.2 |
Hs.694776 |
225 |
regulation of progression through cell cycle transcription regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter caspase activation signal transduction intracellular signaling cascade I-kappaB kinase/NF-kappaB cascade tyrosine phosphorylation of STAT protein STAT protein nuclear translocation response to virus nucleus nucleus cytoplasm transcription factor activity transcription factor activity signal transducer activity hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity calcium ion binding protein binding |
Toll-like receptor signaling pathway Jak-STAT signaling pathway Pancreatic cancer |
| 1 |
5087 |
33355_at |
PBX1 |
pre-B-cell leukemia homeobox 1 |
1 |
162795560 |
AL049381 |
5087 |
1q23 |
Hs.654412 |
41 |
regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter C21-steroid hormone biosynthetic process sex differentiation embryonic development cell differentiation hindbrain development regulation of transcriptional preinitiation complex assembly nucleus nucleus transcription factor activity transcription factor activity protein binding protein binding sequence-specific DNA binding |
|
| 1 |
171546 |
33399_at |
C14orf147 |
chromosome 14 open reading frame 147 |
14 |
-33971895 |
AA142942 |
171546 |
14q13.1 |
Hs.269909 |
3 |
membrane integral to membrane |
|
| 1 |
6935 |
33439_at |
ZEB1 |
zinc finger E-box binding homeobox 1 |
10 |
31648147 |
D15050 |
6935 |
10p11.2 |
Hs.124503 |
29 |
negative regulation of transcription from RNA polymerase II promoter transcription regulation of transcription, DNA-dependent immune response central nervous system development cell proliferation embryonic morphogenesis intracellular nucleus nucleic acid binding transcription factor activity transcription factor activity transcription coactivator activity transcription corepressor activity zinc ion binding zinc ion binding sequence-specific DNA binding metal ion binding |
|
| 1 |
5327 |
33452_at |
PLAT |
plasminogen activator, tissue |
8 |
-42151392 |
M15518 |
5327 |
8p12 |
Hs.491582 |
141 |
protein modification process proteolysis proteolysis blood coagulation extracellular region peptidase activity plasminogen activator activity |
Complement and coagulation cascades |
| 1 |
3312 |
33820_g_at |
HSPA8 |
heat shock 70kDa protein 8 |
11 |
-122433410 |
X13794 |
3312 |
11q24.1 |
Hs.180414 |
96 |
protein folding response to unfolded protein intracellular cytoplasm cell surface nucleotide binding protein binding ATP binding ATPase activity, coupled |
|
| 1 |
60481 |
33821_at |
ELOVL5 |
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) |
6 |
-53240154 |
AL034374 |
60481 |
6p21.1-p12.1 |
Hs.520189 |
10 |
fatty acid biosynthetic process endoplasmic reticulum membrane integral to membrane |
|
| 1 |
3187 |
33845_at |
HNRPH1 |
heterogeneous nuclear ribonucleoprotein H1 (H) |
5 |
-178973785 |
W28483 |
3187 |
5q35.3 |
Hs.604001 |
26 |
mRNA processing RNA splicing nucleus spliceosome heterogeneous nuclear ribonucleoprotein complex nucleotide binding nucleic acid binding RNA binding protein binding poly(U) binding |
|
| 1 |
2817 |
33929_at |
GPC1 |
glypican 1 |
2 |
241023787 |
X54232 |
2817 |
2q35-q37 |
Hs.328232 |
24 |
proteinaceous extracellular matrix extracellular space integral to plasma membrane membrane GPI anchor binding |
|
| 1 |
10406 |
33933_at |
WFDC2 |
WAP four-disulfide core domain 2 |
20 |
43531807 |
X63187 |
10406 |
20q12-q13.2 |
Hs.2719 |
16 |
proteolysis spermatogenesis extracellular region extracellular space serine-type endopeptidase inhibitor activity |
|
| 1 |
9375 |
34307_at |
TM9SF2 |
transmembrane 9 superfamily member 2 |
13 |
98951728 |
U81006 |
9375 |
13q32.3 |
Hs.654824 |
9 |
transport endosome integral to plasma membrane membrane |
|
| 1 |
8334 |
34308_at |
HIST1H2AC |
histone cluster 1, H2ac |
6 |
26232351 |
U90551 |
8334 |
6p21.3 |
Hs.656746 |
19 |
nucleosome assembly chromosome organization and biogenesis (sensu Eukaryota) nucleosome nucleus chromosome DNA binding |
|
| 1 |
6696 |
34342_s_at |
SPP1 |
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) |
4 |
89115825 |
AF052124 |
6696 |
4q21-q25 |
Hs.313 |
162 |
ossification cell adhesion cell-matrix adhesion negative regulation of bone mineralization proteinaceous extracellular matrix extracellular space cytokine activity integrin binding protein binding |
Cell Communication Focal adhesion ECM-receptor interaction Toll-like receptor signaling pathway |
| 1 |
6414 |
34363_at |
SEPP1 |
selenoprotein P, plasma, 1 |
5 |
-42835739, -42835738 |
Z11793 |
6414 |
5q31 |
Hs.275775 Hs.653366 |
22 |
selenium metabolic process response to oxidative stress brain development locomotory behavior post-embryonic development sexual reproduction growth extracellular region extracellular space selenium binding |
|
| 1 |
6391 |
34385_at |
SDHC |
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
1 |
159550789 |
U57877 |
6391 |
1q23.3 |
Hs.444472 |
15 |
tricarboxylic acid cycle tricarboxylic acid cycle electron transport electron transport transport mitochondrion membrane integral to membrane respiratory chain complex II succinate dehydrogenase activity iron ion binding metal ion binding |
Citrate cycle (TCA cycle) Oxidative phosphorylation |
| 1 |
5538 |
34774_at |
PPT1 |
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) |
1 |
-40310970 |
U44772 |
5538 |
1p32 |
Hs.3873 |
34 |
protein depalmitoylation protein depalmitoylation DNA fragmentation during apoptosis protein modification process receptor-mediated endocytosis pinocytosis lysosomal lumen acidification nervous system development brain development brain development visual perception protein transport lipid catabolic process sphingolipid catabolic process protein catabolic process negative regulation of cell growth lipid raft organization and biogenesis negative regulation of neuron apoptosis positive regulation of receptor mediated endocytosis positive regulation of pinocytosis neuron development regulation of synapse structure and activity response to stimulus cofactor transport cofactor metabolic process extracellular region extracellular region membrane fraction nucleus lysosome lysosome Golgi apparatus cytosol synaptic vesicle axon lipid raft palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity palmitoyl-CoA hydrolase activity palmitoyl-CoA hydrolase activity hydrolase activity |
Fatty acid elongation in mitochondria |
| 1 |
8763 |
34819_at |
CD164 |
CD164 molecule, sialomucin |
6 |
-109794415 |
D14043 |
8763 |
6q21 |
Hs.520313 |
12 |
immune response cell adhesion heterophilic cell adhesion negative regulation of cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation negative regulation of cell proliferation hemopoiesis membrane fraction soluble fraction endosome plasma membrane integral to plasma membrane integral to plasma membrane |
|
| 1 |
10916 |
34859_at |
MAGED2 |
melanoma antigen family D, 2 |
X |
54852217, 54850895, 54851521 |
Z98046 |
10916 |
Xp11.2 |
Hs.522665 |
11 |
|
|
| 1 |
10916 |
34860_g_at |
MAGED2 |
melanoma antigen family D, 2 |
X |
54852217, 54850895, 54851521 |
Z98046 |
10916 |
Xp11.2 |
Hs.522665 |
11 |
|
|
| 1 |
771 |
35275_at |
CA12 |
carbonic anhydrase XII |
15 |
-61402783 |
AL050025 |
771 |
15q22 |
Hs.210995 |
22 |
one-carbon compound metabolic process membrane integral to membrane carbonate dehydratase activity zinc ion binding lyase activity metal ion binding |
Nitrogen metabolism |
| 1 |
987 |
35371_at |
LRBA |
LPS-responsive vesicle trafficking, beach and anchor containing |
4 |
-151405045 |
M83822 |
987 |
4q31.3 |
Hs.480938 |
8 |
biological_process cellular_component cytoplasmic membrane-bound vesicle molecular_function protein binding |
|
| 1 |
89927 |
35742_at |
C16orf45 |
chromosome 16 open reading frame 45 |
16 |
15435825 |
U95740 |
89927 |
16p13.11 |
Hs.460095 |
4 |
protein binding |
|
| 1 |
27020 |
35747_at |
NPTN |
neuroplastin |
15 |
-71639410 |
AF035287 |
27020 |
15q22 |
Hs.187866 |
9 |
homophilic cell adhesion positive regulation of long-term neuronal synaptic plasticity integral to membrane presynaptic membrane cell adhesion molecule binding |
|
| 1 |
10972 |
35754_at |
TMED10 |
transmembrane emp24-like trafficking protein 10 (yeast) |
14 |
-74667923 |
L40391 |
10972 |
14q24.3 |
Hs.74137 Hs.684601 |
18 |
ER to Golgi vesicle-mediated transport protein transport regulated secretory pathway vesicle targeting, to, from or within Golgi microsome ER-Golgi intermediate compartment cis-Golgi network membrane integral to membrane zymogen granule membrane protein binding |
|
| 1 |
3875 |
35766_at |
KRT18 |
keratin 18 |
12 |
51629109, 51628921 |
X12883 |
3875 |
12q13 |
Hs.406013 |
81 |
cell cycle anatomical structure morphogenesis Golgi to plasma membrane CFTR protein transport cytoplasm keratin filament structural constituent of cytoskeleton protein binding |
Cell Communication Pathogenic Escherichia coli infection - EHEC Pathogenic Escherichia coli infection - EPEC |
| 1 |
9908 |
35793_at |
G3BP2 |
GTPase activating protein (SH3 domain) binding protein 2 |
4 |
-76786990 |
AB014560 |
9908 |
4q21.1 |
Hs.303676 |
13 |
transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction mRNA transport intracellular cytoplasm nucleotide binding RNA binding protein binding receptor signaling complex scaffold activity |
|
| 1 |
1535 |
35807_at |
CYBA |
cytochrome b-245, alpha polypeptide |
16 |
-87237198 |
M21186 |
1535 |
16q24 |
Hs.513803 |
74 |
electron transport superoxide metabolic process transport cytoplasm mitochondrion membrane iron ion binding protein binding electron carrier activity heme binding metal ion binding |
Leukocyte transendothelial migration |
| 1 |
6385 |
35844_at |
SDC4 |
syndecan 4 |
20 |
-43387344 |
D79206 |
6385 |
20q12 |
Hs.632267 |
48 |
biological_process integral to plasma membrane cell surface membrane molecular_function cytoskeletal protein binding |
ECM-receptor interaction Cell adhesion molecules (CAMs) |
| 1 |
5868 |
36110_at |
RAB5A |
RAB5A, member RAS oncogene family |
3 |
19963762 |
M28215 |
5868 |
3p24-p22 |
Hs.475663 |
52 |
endocytosis small GTPase mediated signal transduction protein transport ruffle early endosome plasma membrane endocytic vesicle lipid raft nucleotide binding GTPase activity protein binding protein binding GTP binding |
Amyotrophic lateral sclerosis (ALS) |
| 1 |
1832 |
36133_at |
DSP |
desmoplakin |
6 |
7486868 |
AL031058 |
1832 |
6p24 |
Hs.519873 |
52 |
epidermis development peptide cross-linking keratinocyte differentiation cornified envelope cytoplasm intermediate filament cell-cell adherens junction structural constituent of cytoskeleton protein binding, bridging |
|
| 1 |
9806 |
36155_at |
SPOCK2 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
10 |
-73488798 |
D87465 |
9806 |
10pter-q25.3 |
Hs.523009 |
9 |
synaptogenesis extracellular matrix organization and biogenesis regulation of cell differentiation proteinaceous extracellular matrix calcium ion binding |
|
| 1 |
163 |
36161_at |
AP2B1 |
adaptor-related protein complex 2, beta 1 subunit |
17 |
30938394 |
M34175 |
163 |
17q11.2-q12 |
Hs.514819 |
28 |
protein complex assembly intracellular protein transport vesicle-mediated transport membrane membrane coat clathrin adaptor complex protein binding protein binding protein transporter activity |
|
| 1 |
1345 |
36165_at |
COX6C |
cytochrome c oxidase subunit VIc |
8 |
-100959547 |
W51774 |
1345 |
8q22-q23 |
Hs.351875 |
8 |
electron transport mitochondrion membrane integral to membrane cytochrome-c oxidase activity oxidoreductase activity |
Oxidative phosphorylation |
| 1 |
10923 |
36171_at |
SUB1 |
SUB1 homolog (S. cerevisiae) |
5 |
32621433 |
AI521453 |
10923 |
5p13.3 |
Hs.229641 |
28 |
transcription regulation of transcription from RNA polymerase II promoter transcription factor complex DNA binding single-stranded DNA binding transcription coactivator activity protein binding |
|
| 1 |
9804 |
36198_at |
TOMM20 |
translocase of outer mitochondrial membrane 20 homolog (yeast) |
1 |
-233339282 |
D13641 |
9804 |
1q42 |
Hs.533192 |
22 |
protein targeting to mitochondrion protein import into mitochondrion mitochondrion mitochondrial outer membrane translocase complex membrane integral to membrane outer membrane protein transmembrane transporter activity unfolded protein binding |
|
| 1 |
7277 |
36591_at |
TUBA4A |
tubulin, alpha 4a |
2 |
-219823244 |
X06956 |
7277 |
2q35 |
Hs.75318 |
66 |
microtubule-based movement protein polymerization microtubule protein complex nucleotide binding GTPase activity structural molecule activity protein binding GTP binding |
Gap junction Pathogenic Escherichia coli infection - EHEC Pathogenic Escherichia coli infection - EPEC |
| 1 |
8404 |
36627_at |
SPARCL1 |
SPARC-like 1 (mast9, hevin) |
4 |
-88613511 |
X86693 |
8404 |
4q22.1 |
Hs.62886 |
11 |
proteinaceous extracellular matrix calcium ion binding |
|
| 1 |
10928 |
36628_at |
RALBP1 |
ralA binding protein 1 |
18 |
9465529 |
L42542 |
10928 |
18p11.3 |
Hs.528993 |
30 |
transport chemotaxis signal transduction signal transduction small GTPase mediated signal transduction regulation of GTPase activity positive regulation of Cdc42 GTPase activity intracellular membrane GTPase activator activity protein binding ATPase activity Ral GTPase binding Rac GTPase activator activity ATPase activity, coupled to movement of substances Rac GTPase binding |
Pancreatic cancer |
| 1 |
7832 |
36634_at |
BTG2 |
BTG family, member 2 |
1 |
201541286 |
U72649 |
7832 |
1q32 |
Hs.519162 |
36 |
DNA repair transcription regulation of transcription, DNA-dependent protein amino acid methylation negative regulation of cell proliferation anterior/posterior pattern formation transcription factor activity protein binding |
|
| 1 |
4942 |
36636_at |
OAT |
ornithine aminotransferase (gyrate atrophy) |
10 |
-126075861 |
M12267 |
4942 |
10q26 |
Hs.523332 |
28 |
amino acid metabolic process ornithine metabolic process visual perception mitochondrion mitochondrial matrix ornithine-oxo-acid transaminase activity protein binding transferase activity pyridoxal phosphate binding |
Arginine and proline metabolism |
| 1 |
1490 |
36638_at |
CTGF |
connective tissue growth factor |
6 |
-132311011 |
X78947 |
1490 |
6q23.1 |
Hs.591346 |
116 |
cartilage condensation ossification angiogenesis regulation of cell growth DNA replication cell adhesion cell-matrix adhesion integrin-mediated signaling pathway fibroblast growth factor receptor signaling pathway epidermis development response to wounding cell migration cell differentiation extracellular region proteinaceous extracellular matrix extracellular space soluble fraction plasma membrane integrin binding protein binding insulin-like growth factor binding heparin binding |
|
| 1 |
55699 |
36647_at |
IARS2 |
isoleucyl-tRNA synthetase 2, mitochondrial |
1 |
218334077 |
AA526812 |
55699 |
1q41 |
Hs.262823 |
5 |
isoleucyl-tRNA aminoacylation cytoplasm mitochondrion nucleotide binding isoleucine-tRNA ligase activity ATP binding zinc ion binding ligase activity |
Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis |
| 1 |
1718 |
36658_at |
DHCR24 |
24-dehydrocholesterol reductase |
1 |
-55087887 |
D13643 |
1718 |
1p33-p31.1 |
Hs.498727 |
14 |
electron transport cholesterol biosynthetic process cholesterol biosynthetic process apoptosis anti-apoptosis response to oxidative stress cell cycle arrest protein localization tissue development membrane organization and biogenesis male genitalia development plasminogen activation amyloid precursor protein catabolic process negative regulation of caspase activity neuroprotection skin development nucleus endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor enzyme binding peptide antigen binding |
Biosynthesis of steroids |
| 1 |
427 |
36938_at |
ASAH1 |
N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
8 |
-17958213 |
U70063 |
427 |
8p22-p21.3 |
Hs.527412 |
22 |
fatty acid metabolic process ceramide metabolic process carboxylic acid metabolic process lysosome hydrolase activity ceramidase activity transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
Sphingolipid metabolism |
| 1 |
1859 |
36946_at |
DYRK1A |
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
21 |
37714470, 37714471, 37713076, 37661728 |
D86550 |
1859 |
21q22.13 |
Hs.368240 |
40 |
nervous system development peptidyl-tyrosine phosphorylation protein amino acid autophosphorylation nucleus nuclear speck nucleotide binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding kinase activity transferase activity protein self-association |
|
| 1 |
51669 |
36975_at |
TMEM66 |
transmembrane protein 66 |
8 |
-30040173 |
W26659 |
51669 |
8p12 |
Hs.521487 |
9 |
membrane integral to membrane |
|
| 1 |
6726 |
36981_at |
SRP9 |
signal recognition particle 9kDa |
1 |
224032153 |
AF070649 |
6726 |
1q42.12 |
Hs.511425 Hs.642815 |
9 |
SRP-dependent cotranslational protein targeting to membrane negative regulation of translational elongation cytoplasm signal recognition particle receptor complex signal recognition particle, endoplasmic reticulum targeting signal recognition particle signal recognition particle binding protein binding 7S RNA binding |
Protein export |
| 1 |
25874 |
37000_at |
BRP44 |
brain protein 44 |
1 |
-166153933 |
AL035304 |
25874 |
1q24 |
Hs.517768 |
9 |
mitochondrion |
|
| 1 |
3936 |
37023_at |
LCP1 |
lymphocyte cytosolic protein 1 (L-plastin) |
13 |
-45598059 |
J02923 |
3936 |
13q14.3 |
Hs.381099 |
33 |
biological_process actin filament bundle formation ruffle phagocytic cup cytoplasm cytosol actin filament actin binding calcium ion binding calcium ion binding identical protein binding actin filament binding |
|
| 1 |
27230 |
37035_at |
SERP1 |
stress-associated endoplasmic reticulum protein 1 |
3 |
-151742470 |
AI557272 |
27230 |
3q25.1 |
Hs.518326 |
10 |
protein amino acid glycosylation protein targeting response to stress plasma membrane organization and biogenesis protein transport endoplasmic reticulum ribosome membrane integral to membrane |
|
| 1 |
5825 |
37038_at |
ABCD3 |
ATP-binding cassette, sub-family D (ALD), member 3 |
1 |
94656598 |
X83467 |
5825 |
1p22-p21 |
Hs.76781 |
21 |
transport peroxisome organization and biogenesis peroxisomal long-chain fatty acid import mitochondrion mitochondrial inner membrane peroxisome peroxisomal membrane integral to peroxisomal membrane membrane integral to membrane nucleotide binding protein binding ATP binding ATPase activity ATPase activity, coupled to transmembrane movement of substances |
ABC transporters - General |
| 1 |
9794 |
37292_at |
MAML1 |
mastermind-like 1 (Drosophila) |
5 |
179092456 |
D83785 |
9794 |
5q35 |
Hs.631951 |
13 |
transcription regulation of transcription, DNA-dependent Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter nucleus transcription coactivator activity |
Notch signaling pathway |
| 1 |
10951 |
37304_at |
CBX1 |
chromobox homolog 1 (HP1 beta homolog Drosophila ) |
17 |
-43502421 |
U35451 |
10951 |
17q |
Hs.77254 |
35 |
chromatin assembly or disassembly chromatin female pronucleus male pronucleus nucleus nucleoplasm polytene chromosome chromocenter nuclear heterochromatin centric heterochromatin chromatin binding identical protein binding |
|
| 1 |
8659 |
37332_r_at |
ALDH4A1 |
aldehyde dehydrogenase 4 family, member A1 |
1 |
-19070512 |
U24267 |
8659 |
1p36 |
Hs.77448 |
12 |
proline biosynthetic process proline catabolic process metabolic process mitochondrion mitochondrial matrix 1-pyrroline-5-carboxylate dehydrogenase activity aldehyde dehydrogenase (NAD) activity electron carrier activity oxidoreductase activity |
Glutamate metabolism Arginine and proline metabolism |
| 1 |
3108 |
37344_at |
HLA-DMA |
major histocompatibility complex, class II, DM alpha |
6 |
-33024373, -4297248, -4102468 |
X62744 |
3108 |
6p21.3 |
Hs.351279 |
40 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II immune response biological_process antigen processing and presentation cellular_component lysosome endosome membrane integral to membrane MHC class II protein complex protein binding MHC class II receptor activity |
Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus |
| 1 |
3280 |
37393_at |
HES1 |
hairy and enhancer of split 1, (Drosophila) |
3 |
195336627 |
L19314 |
3280 |
3q28-q29 |
Hs.250666 |
27 |
negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-dependent cell adhesion nervous system development positive regulation of cell proliferation lung development auditory receptor cell differentiation auditory receptor cell fate determination cell fate commitment negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation cell maturation nucleus cytoplasm DNA binding transcription repressor activity |
Notch signaling pathway Maturity onset diabetes of the young |
| 1 |
8991 |
37405_at |
SELENBP1 |
selenium binding protein 1 |
1 |
-149603404 |
U29091 |
8991 |
1q21-q22 |
Hs.632460 |
13 |
protein transport cytoplasm membrane selenium binding selenium binding |
|
| 1 |
23429 |
37732_at |
RYBP |
RING1 and YY1 binding protein |
3 |
-72506440 |
AL049940 |
|