Identified probes

Factor ENTREZ.ID Probe Symbol Description Chromosome Chromosome Location GenBank Gene Cytoband UniGene PubMed Gene Ontology Pathway
1 31315_at IGL@ immunoglobulin lambda locus 22   D84143 22q11.1-q11.2 Hs.449585 14    
1 31319_at         M20707          
1 31364_i_at NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 16 68156497 W27762 16q22.1 Hs.371987 30

cytokine production

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

signal transduction

excretion

positive regulation of transcription from RNA polymerase II promoter

nucleus

cytoplasm

transcription factor activity

RNA polymerase II transcription factor activity

protein binding

Wnt signaling pathway

Axon guidance

VEGF signaling pathway

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

B cell receptor signaling pathway

1 31510_s_at H3F3B H3 histone, family 3B (H3.3B) 17 -71284111 Z48950 17q25 Hs.180877 21

nucleosome assembly

chromosome organization and biogenesis (sensu Eukaryota)

nucleosome

nucleus

chromosome

DNA binding

 
1 31536_at RTN4 reticulon 4 2 -55052832 AB020693 2p16.3 Hs.645283 54

negative regulation of anti-apoptosis

negative regulation of axon extension

regulation of apoptosis

nuclear envelope

endoplasmic reticulum

endoplasmic reticulum

membrane

integral to membrane

integral to endoplasmic reticulum membrane

protein binding

 
1 31692_at HSPA1B heat shock 70kDa protein 1B 6 3043121 M59830 6p21.3 Hs.274402 50

mRNA catabolic process

protein folding

anti-apoptosis

response to unfolded protein

nucleus

cytoplasm

mitochondrion

endoplasmic reticulum

nucleotide binding

ATP binding

unfolded protein binding

 
1 34095_f_at ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 7 98810264 U80114 7q22.1 Hs.449574 Hs.489284 Hs.503878 Hs.533963 23

cell motility

cell adhesion

Arp2/3 protein complex

membrane

structural constituent of cytoskeleton

protein binding

Regulation of actin cytoskeleton

1 35566_f_at IL8 interleukin 8 4 74825138 AF015128 4q13-q21 Hs.624 Hs.449585 Hs.551925 Hs.561078 Hs.654584 480

angiogenesis

cell motility

chemotaxis

inflammatory response

immune response

cell cycle arrest

G-protein coupled receptor protein signaling pathway

intracellular signaling cascade

cell-cell signaling

negative regulation of cell proliferation

calcium-mediated signaling

regulation of cell adhesion

neutrophil chemotaxis

neutrophil activation

regulation of retroviral genome replication

induction of positive chemotaxis

extracellular region

extracellular space

interleukin-8 receptor binding

protein binding

chemokine activity

Cytokine-cytokine receptor interaction

Toll-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Bladder cancer

1 36347_f_at HIST1H2BN histone cluster 1, H2bn 6 27914418 Z98744 6p22-p21.3 Hs.673851 18

nucleosome assembly

chromosome organization and biogenesis (sensu Eukaryota)

nucleosome

nucleus

chromosome

DNA binding

 
1 35926_s_at LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 19 59833779, 59833719, 59820440 AF009005 19q13.4 Hs.655593 Hs.667388 37

immune response

response to virus

membrane

integral to membrane

receptor activity

protein phosphatase 1 binding

 
1 36773_f_at HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 6 -32735634 M81141 6p21.3 Hs.409934 Hs.534322 Hs.653339 161

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

immune response

immune response

cell cycle

membrane

membrane

integral to membrane

MHC class II protein complex

GTP binding

MHC class II receptor activity

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Type I diabetes mellitus

1 36790_at TPM1 tropomyosin 1 (alpha) 15 61121890, 61127688 M19267 15q22.1 Hs.133892 60

cell motility

regulation of muscle contraction

regulation of heart contraction

cytoplasm

cytoskeleton

muscle thin filament tropomyosin

actin binding

structural constituent of cytoskeleton

structural constituent of muscle

 
1 36791_g_at TPM1 tropomyosin 1 (alpha) 15 61121890, 61127688 M19267 15q22.1 Hs.133892 60

cell motility

regulation of muscle contraction

regulation of heart contraction

cytoplasm

cytoskeleton

muscle thin filament tropomyosin

actin binding

structural constituent of cytoskeleton

structural constituent of muscle

 
1 36792_at TPM1 tropomyosin 1 (alpha) 15 61121890, 61127688 Z24727 15q22.1 Hs.133892 60

cell motility

regulation of muscle contraction

regulation of heart contraction

cytoplasm

cytoskeleton

muscle thin filament tropomyosin

actin binding

structural constituent of cytoskeleton

structural constituent of muscle

 
1 37411_at CENTB1 centaurin, beta 1 17 7180596 D30758 17p13.1 Hs.337242 10

intracellular signaling cascade

regulation of GTPase activity

phospholipase C activity

GTPase activator activity

zinc ion binding

metal ion binding

 
1 37420_i_at HLA-F major histocompatibility complex, class I, F 6 945922, 1143812, 29799095 X17093 6p21.3 Hs.519972 51

antigen processing and presentation of peptide antigen via MHC class I

immune response

antigen processing and presentation

membrane

integral to membrane

MHC class I protein complex

MHC class I receptor activity

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Type I diabetes mellitus

1 37467_at IGHD immunoglobulin heavy constant delta 14   K02882 14q32.33 Hs.510635 17

immune response

antigen binding

 
1 38545_at INHBB inhibin, beta B 2 120820188 M31682 2cen-q13 Hs.1735 46

ovarian follicle development

defense response

response to external stimulus

cell differentiation

growth

positive regulation of follicle-stimulating hormone secretion

negative regulation of follicle-stimulating hormone secretion

negative regulation of hepatocyte growth factor biosynthetic process

extracellular region

cytokine activity

hormone activity

growth factor activity

protein homodimerization activity

host cell surface receptor binding

Cytokine-cytokine receptor interaction

TGF-beta signaling pathway

1 39610_at HOXB2 homeobox B2 17 -43975019 X16665 17q21-q22 Hs.514289 21

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

multicellular organismal development

multicellular organismal development

circulation

nucleus

nucleus

transcription factor activity

transcription factor activity

sequence-specific DNA binding

 
1 39994_at CCR1 chemokine (C-C motif) receptor 1 3 -46218203 D10925 3p21 Hs.301921 58

chemotaxis

inflammatory response

immune response

cell adhesion

G-protein signaling, coupled to cyclic nucleotide second messenger

elevation of cytosolic calcium ion concentration

cell-cell signaling

cytokine and chemokine mediated signaling pathway

plasma membrane

plasma membrane

integral to plasma membrane

rhodopsin-like receptor activity

receptor activity

protein binding

C-C chemokine receptor activity

Cytokine-cytokine receptor interaction

1 40729_s_at LTB lymphotoxin beta (TNF superfamily, member 3) 6 -31656316, -2994460, -2795924 Y14768 6p21.3 Hs.376208 31

immune response

signal transduction

cell-cell signaling

cellular_component

extracellular space

membrane

integral to membrane

cytokine activity

tumor necrosis factor receptor binding

Cytokine-cytokine receptor interaction

1 40738_at CD2 CD2 molecule 1 117098608 M16336 1p13 Hs.523500 65

lipid raft polarization

induction of apoptosis

cell surface receptor linked signal transduction

cell-cell adhesion

natural killer cell activation

positive regulation of myeloid dendritic cell activation

T cell activation

regulation of T cell differentiation

integral to plasma membrane

membrane

receptor activity

protein binding

protein binding

Cell adhesion molecules (CAMs)

Hematopoietic cell lineage

1 41447_at CHSY1 carbohydrate (chondroitin) synthase 1 15 -99533455 AB023207 15q26.3 Hs.110488 8

membrane

integral to membrane

transferase activity

metal ion binding

glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

Chondroitin sulfate biosynthesis

Glycan structures - biosynthesis 1

1 41609_at HLA-DMB major histocompatibility complex, class II, DM beta 6 -33010393, -4088489 U15085 6p21.3 Hs.654428 46

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

immune response

lysosome

endosome

membrane

integral to membrane

MHC class II protein complex

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Type I diabetes mellitus

1 41660_at CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) 22 -45135394 AL031588 22q13.3 Hs.252387 11

neural tube closure

homophilic cell adhesion

signal transduction

neuropeptide signaling pathway

multicellular organismal development

central nervous system development

central nervous system development

locomotory behavior

establishment of polarity of embryonic epithelium

inner ear morphogenesis

apical protein localization

integral to plasma membrane

membrane

G-protein coupled receptor activity

calcium ion binding

protein dimerization activity

 
1 31820_at HCLS1 hematopoietic cell-specific Lyn substrate 1 3 -122832936 X16663 3q13 Hs.14601 30

regulation of transcription, DNA-dependent

intracellular signaling cascade

positive regulation of cell proliferation

response to hormone stimulus

erythrocyte differentiation

positive regulation of tyrosine phosphorylation of STAT protein

nucleus

DNA-directed RNA polymerase II, core complex

cytoplasm

mitochondrion

membrane

transcription factor activity

protein binding

SH3 domain binding

Tight junction

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

1 31870_at CD37 CD37 molecule 19 54530488 X14046 19q13.3 Hs.166556 16

protein amino acid N-linked glycosylation

plasma membrane

integral to plasma membrane

membrane

integral to membrane

Hematopoietic cell lineage

1 32034_at ZNF217 zinc finger protein 217 20 -51617018 AF041259 20q13.2 Hs.155040 13

regulation of transcription, DNA-dependent

intracellular

transcription factor activity

zinc ion binding

metal ion binding

 
1 32070_at PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 11 -66959556 X97267 11q13.3 Hs.155975 10

defense response

plasma membrane

integral to plasma membrane

 
1 32119_at         AL049423          
1 32736_at RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 22 -35951257 W68830 22q13.1 Hs.517601 44

chemotaxis

signal transduction

small GTPase mediated signal transduction

cell projection biogenesis

actin cytoskeleton organization and biogenesis

intracellular

membrane fraction

nuclear envelope

cytoplasm

nucleotide binding

GTPase activity

protein binding

GTP binding

MAPK signaling pathway

Wnt signaling pathway

Axon guidance

VEGF signaling pathway

Focal adhesion

Adherens junction

Natural killer cell mediated cytotoxicity

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Leukocyte transendothelial migration

Regulation of actin cytoskeleton

Colorectal cancer

Pancreatic cancer

1 33219_at USP33 ubiquitin specific peptidase 33 1 -77934263, -77949927 AB029020 1p31.1 Hs.480597 11

ubiquitin-dependent protein catabolic process

protein deubiquitination

protein deubiquitination

cytoplasm

VCB complex

ubiquitin thiolesterase activity

protein binding

protein binding

cysteine-type peptidase activity

zinc ion binding

metal ion binding

 
1 33730_at GPRC5A G protein-coupled receptor, family C, group 5, member A 12 12935222 AF095448 12p13-p12.3 Hs.631733 12

signal transduction

G-protein coupled receptor protein signaling pathway

integral to plasma membrane

membrane

cytoplasmic vesicle

receptor activity

metabotropic glutamate, GABA-B-like receptor activity

 
1 34677_f_at LOC220594 TL132 protein 17   AJ012755 17p11.2 Hs.234573 Hs.462475 2

ubiquitin-dependent protein catabolic process

ubiquitin thiolesterase activity

 
1 34678_at FER1L3 fer-1-like 3, myoferlin (C. elegans) 10 -95056175 AL096713 10q24 Hs.655278 11

muscle contraction

circulation

nuclear envelope

plasma membrane

integral to membrane

 
1 34759_at SLC30A1 solute carrier family 30 (zinc transporter), member 1 1 -209815005 U68494 1q32-q41 Hs.519469 4

in utero embryonic development

cation transport

zinc ion transport

cellular zinc ion homeostasis

nutrient import

membrane

integral to membrane

zinc ion binding

cation transmembrane transporter activity

 
1 35168_f_at COL16A1 collagen, type XVI, alpha 1 1 -31890434 M92642 1p35-p34 Hs.368921 10

phosphate transport

cell adhesion

integrin-mediated signaling pathway

female pregnancy

proteinaceous extracellular matrix

collagen type XVI

cytoplasm

integrin binding

structural molecule activity

protein binding

 
1 35207_at SCNN1A sodium channel, nonvoltage-gated 1 alpha 12 -6326275 X76180 12p13 Hs.591047 42

ion transport

sodium ion transport

excretion

response to stimulus

membrane fraction

integral to plasma membrane

membrane

ion channel activity

protein binding

amiloride-sensitive sodium channel activity

sodium ion binding

Taste transduction

1 35214_at UGDH UDP-glucose dehydrogenase 4 -39176770 AF061016 4p15.1 Hs.572518 17

UDP-glucose metabolic process

glycosaminoglycan biosynthetic process

UDP-glucuronate biosynthetic process

electron transport

gastrulation (sensu Mammalia)

UDP-glucose 6-dehydrogenase activity

electron carrier activity

NAD binding

Pentose and glucuronate interconversions

Ascorbate and aldarate metabolism

Starch and sucrose metabolism

Nucleotide sugars metabolism

1 35238_at TRAF5 TNF receptor-associated factor 5 1 209566579, 209586328, 209566801 AB000509 1q32 Hs.523930 44

signal transduction

regulation of apoptosis

positive regulation of I-kappaB kinase/NF-kappaB cascade

cytoplasm

signal transducer activity

protein binding

protein binding

zinc ion binding

metal ion binding

Small cell lung cancer

1 35656_at RNF6 ring finger protein (C3H2C3 type) 6 13 -25684905, -25684904 AJ010346 13q12.2 Hs.136885 6

ubiquitin-dependent protein catabolic process

biological_process

negative regulation of axon extension

positive regulation of transcription, DNA-dependent

cellular_component

cytoplasm

PML body

axon

DNA binding

ubiquitin-protein ligase activity

protein binding

zinc ion binding

transcription activator activity

metal ion binding

 
1 36493_at LSP1 lymphocyte-specific protein 1 11 1846478, 1848674, 1848729, 1830775 M33552 11p15.5 Hs.56729 23

cell motility

cellular defense response

signal transduction

actin cytoskeleton

membrane

actin binding

signal transducer activity

 
1 36499_at CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 1 109594163 D87469 1p21 Hs.57652 6

homophilic cell adhesion

signal transduction

neuropeptide signaling pathway

multicellular organismal development

membrane

integral to membrane

receptor activity

G-protein coupled receptor activity

G-protein coupled receptor activity

calcium ion binding

 
1 36550_at RIN2 Ras and Rab interactor 2 20 19818209 AL049538 20p11.22 Hs.472270 7

endocytosis

small GTPase mediated signal transduction

cellular_component

cytoplasm

small GTPase regulator activity

GTPase activator activity

Rab guanyl-nucleotide exchange factor activity

 
1 36827_at ACBD3 acyl-Coenzyme A binding domain containing 3 1 -224399004 AF020762 1q42.12 Hs.520207 10

steroid biosynthetic process

transport

mitochondrion

membrane

integral to membrane

acyl-CoA binding

binding

 
1 36890_at PPL periplakin 16 -4872508 AF001691 16p13.3 Hs.192233 24

keratinization

cytoplasm

mitochondrion

cytoskeleton

cell junction

structural constituent of cytoskeleton

protein binding

 
1 36909_at WEE1 WEE1 homolog (S. pombe) 11 9550915 X62048 11p15.3-p15.1 Hs.249441 48

regulation of progression through cell cycle

protein amino acid phosphorylation

cell cycle

mitosis

cell division

nucleus

nucleotide binding

magnesium ion binding

protein serine/threonine kinase activity

protein-tyrosine kinase activity

protein binding

ATP binding

transferase activity

Cell cycle

1 37242_at FTO fat mass and obesity associated 16 52295375 U79260 16q12.2 Hs.528833 9

determination of left/right symmetry

embryonic limb morphogenesis

 
1 37897_s_at TFF3 trefoil factor 3 (intestinal) 21 -42605232 AI985964 21q22.3 Hs.82961 39

defense response

digestion

extracellular region

secretory granule

 
1 37900_at PEX11B peroxisomal biogenesis factor 11B 1 144227739 AF093670 1q21.1 Hs.504284 10

peroxisome fission

mitochondrion

peroxisome

peroxisomal membrane

integral to peroxisomal membrane

membrane

integral to membrane

protein binding

 
1 37984_s_at ARF6 ADP-ribosylation factor 6 14 49429485 M57763 14q21.3 Hs.525330 Hs.593068 Hs.694988 67

ER to Golgi vesicle-mediated transport

cell motility

cell adhesion

small GTPase mediated signal transduction

protein transport

vesicle-mediated transport

positive regulation of actin filament polymerization

cortical actin cytoskeleton organization and biogenesis

ruffle organization and biogenesis

regulation of Rac protein signal transduction

negative regulation of receptor mediated endocytosis

ruffle

intracellular

membrane fraction

cytoplasm

endosome

plasma membrane

cell cortex

nucleotide binding

GTPase activity

protein binding

GTP binding

Cholera - Infection

1 38287_at PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 6 32929915, 4202792, 4007991 AA808961 6p21.3 Hs.654585 50

proteolysis

ubiquitin-dependent protein catabolic process

immune response

antigen processing and presentation

cytoplasm

cytosol

proteasome core complex (sensu Eukaryota)

threonine endopeptidase activity

 
1 38317_at TCEAL1 transcription elongation factor A (SII)-like 1 X 102770547, 102770303 M99701 Xq22.1 Hs.95243 10

negative regulation of transcription from RNA polymerase II promoter

transcription

regulation of transcription, DNA-dependent

nucleus

transcription factor activity

RNA polymerase II transcription factor activity

 
1 38324_at LSR lipolysis stimulated lipoprotein receptor 19 40431398 AD000684 19q13.12 Hs.466507 8

liver development

embryonic development

plasma membrane

integral to membrane

chylomicron

receptor activity

lipid transporter activity

 
1 38650_at IGFBP5 insulin-like growth factor binding protein 5 2 -217245073 L27560 2q33-q36 Hs.635441 66

regulation of cell growth

signal transduction

extracellular region

endoplasmic reticulum

insulin-like growth factor binding

 
1 38653_at PMP22 peripheral myelin protein 22 17 -15073821 D11428 17p12-p11.2 Hs.372031 91

synaptic transmission

peripheral nervous system development

sensory perception of sound

mechanosensory behavior

negative regulation of cell proliferation

integral to plasma membrane

membrane

 
1 38976_at CORO1A coronin, actin binding protein, 1A 16 30102426 D44497 16p11.2 Hs.415067 17

transport

cell motility

mitosis

cytoplasm

lysosomal membrane

actin cytoskeleton

membrane

cytoplasmic vesicle

actin binding

structural molecule activity

protein binding

 
1 38990_at FBXO9 F-box protein 9 6 53043729, 53037754, 53038215 AL031178 6p12.3-p11.2 Hs.216653 9

protein ubiquitination

ubiquitin ligase complex

ubiquitin-protein ligase activity

 
1 39012_g_at ENSA endosulfine alpha 1 -148866147, -148861224, -148862378 X99906 1q21.2 Hs.632456 13

transport

response to nutrient

cytoplasm

receptor binding

ion channel inhibitor activity

 
1 39032_at TSC22D1 TSC22 domain family, member 1 13 -43905660 AJ222700 13q14 Hs.507916 17

transcription

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

cytoplasm

transcription factor activity

 
1 39033_at TMEM59 transmembrane protein 59 1 -54269938 Z78368 1p36-p31 Hs.523262 10

membrane

integral to membrane

 
1 39065_s_at TTC3 tetratricopeptide repeat domain 3 21 37377116, 37367440 D83327 21q22.2 Hs.368214 9

biological_process

cellular_component

binding

protein binding

zinc ion binding

metal ion binding

 
1 39331_at TUBB2A tubulin, beta 2A 6 -3098902 X79535 6p25 Hs.654543 71

microtubule-based movement

protein polymerization

cytoplasm

cytoskeleton

microtubule

protein complex

nucleotide binding

GTPase activity

structural constituent of cytoskeleton

protein binding

GTP binding

Gap junction

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

1 39351_at CD59 CD59 molecule, complement regulatory protein 11 -33681133 M84349 11p13 Hs.278573 Hs.653685 Hs.693685 80

defense response

immune response

cell surface receptor linked signal transduction

blood coagulation

membrane fraction

plasma membrane

protein binding

GPI anchor binding

Complement and coagulation cascades

Hematopoietic cell lineage

1 39389_at CD9 CD9 molecule 12 6179815 M38690 12p13.3 Hs.114286 73

cell motility

cell adhesion

fusion of sperm to egg plasma membrane

platelet activation

paranodal junction assembly

plasma membrane

integral to plasma membrane

membrane

integral to membrane

protein binding

Hematopoietic cell lineage

1 39396_at LYPLA1 lysophospholipase I 8 -55121491 AF081281 8q11.23 Hs.435850 11

lipid metabolic process

fatty acid metabolic process

membrane fraction

cytoplasm

lysophospholipase activity

hydrolase activity

Glycerophospholipid metabolism

1 39397_at NR2F2 nuclear receptor subfamily 2, group F, member 2 15 94674949 M64497 15q26 Hs.347991 19

transcription

regulation of transcription, DNA-dependent

regulation of transcription from RNA polymerase II promoter

lipid metabolic process

signal transduction

nucleus

nucleus

transcription factor activity

ligand-regulated transcription factor activity

steroid hormone receptor activity

transcription corepressor activity

zinc ion binding

sequence-specific DNA binding

metal ion binding

 
1 39436_at BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 8 26296439 AF079221 8p21 Hs.131226 15

apoptosis

induction of apoptosis

negative regulation of survival gene product activity

positive regulation of apoptosis

negative regulation of apoptosis

defense response to virus

nuclear envelope

mitochondrion

mitochondrial envelope

endoplasmic reticulum

membrane

integral to membrane

lamin binding

protein homodimerization activity

protein heterodimerization activity

 
1 39685_at ATXN10 ataxin 10 22 44446350 AL050282 22q13.31 Hs.475125 17

biological_process

cell death

cellular_component

cytoplasm

binding

protein binding

 
1 39714_at SH3BGRL SH3 domain binding glutamic acid-rich protein like X 80344277 AF042081 Xq13.3 Hs.108029 10

nucleus

cytoplasm

SH3/SH2 adaptor activity

 
1 39744_at DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked X 41077594 AF000982 Xp11.3-p11.23 Hs.380774 23

nucleus

cytoplasm

nucleotide binding

DNA binding

RNA binding

ATP-dependent RNA helicase activity

ATP binding

hydrolase activity

 
1 39754_at ITGB5 integrin, beta 5 3 -125964485 X53002 3q21.2 Hs.536663 46

cell adhesion

cell-matrix adhesion

integrin-mediated signaling pathway

multicellular organismal development

integrin complex

membrane

integral to membrane

receptor activity

integrin binding

protein binding

Focal adhesion

ECM-receptor interaction

Regulation of actin cytoskeleton

1 39756_g_at XBP1 X-box binding protein 1 22 -27520548 Z93930 22q12.1 22q12 Hs.437638 42

transcription

regulation of transcription, DNA-dependent

immune response

nucleus

transcription factor activity

sequence-specific DNA binding

protein dimerization activity

 
1 40063_at CALCOCO2 calcium binding and coiled-coil domain 2 17 44263370 U22897 17q21.32 Hs.514920 10

viral reproduction

nucleus

cytoplasm

protein binding

 
1 40078_at PRSS23 protease, serine, 23 11 86189138 AF015287 11q14.1 Hs.25338 Hs.694882 13

proteolysis

nucleus

serine-type endopeptidase activity

peptidase activity

 
1 40079_at         AA156240          
1 40091_at BCL6 B-cell CLL/lymphoma 6 (zinc finger protein 51) 3 -188921858 U00115 3q27 Hs.478588 95

protein import into nucleus, translocation

negative regulation of transcription from RNA polymerase II promoter

cell morphogenesis

negative regulation of cell-matrix adhesion

regulation of germinal center formation

negative regulation of T-helper 2 type immune response

negative regulation of B cell apoptosis

transcription

regulation of transcription, DNA-dependent

response to DNA damage stimulus

Rho protein signal transduction

spermatogenesis

protein localization

negative regulation of cell proliferation

actin cytoskeleton organization and biogenesis

B cell differentiation

negative regulation of cell growth

positive regulation of B cell proliferation

regulation of Rho GTPase activity

negative regulation of mast cell cytokine production

negative regulation of Rho protein signal transduction

T-helper 2 type immune response

positive regulation of apoptosis

regulation of memory T cell differentiation

negative regulation of cell differentiation

negative regulation of T-helper 2 cell differentiation

negative regulation of S phase of mitotic cell cycle

negative regulation of isotype switching to IgE isotypes

erythrocyte development

regulation of inflammatory response

regulation of immune response

positive regulation of cell motility

intracellular

nucleus

nucleus

replication fork

DNA binding

chromatin binding

protein binding

zinc ion binding

transcription repressor activity

transcription repressor activity

sequence-specific DNA binding

metal ion binding

 
1 40146_at RAP1B RAP1B, member of RAS oncogene family 12 67290918 AL080212 12q14 Hs.369920 28

small GTPase mediated signal transduction

intracellular

cytoplasm

membrane

nucleotide binding

GTP binding

MAPK signaling pathway

Focal adhesion

Leukocyte transendothelial migration

Long-term potentiation

Renal cell carcinoma

1 40152_r_at PEX5 peroxisomal biogenesis factor 5 12 7234223 Z48054 12p13.3 Hs.567327 39

protein transport

cytoplasm

peroxisome

peroxisomal membrane

membrane

peroxisome matrix targeting signal-1 binding

protein binding

 
1 40422_at IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2 217206371 X16302 2q33-q34 Hs.438102 65

regulation of cell growth

extracellular region

extracellular space

insulin-like growth factor binding

 
1 40499_r_at TUSC4 tumor suppressor candidate 4 3 -50359922 AF040708 3p21.3 Hs.437083 8

cell cycle

negative regulation of progression through cell cycle

protein binding

 
1 40518_at PTPRC protein tyrosine phosphatase, receptor type, C 1 196874759 Y00062 1q31-q32 Hs.654514 131

negative regulation of T cell mediated cytotoxicity

negative regulation of cytokine and chemokine mediated signaling pathway

negative regulation of protein kinase activity

negative regulation of protein kinase activity

protein amino acid dephosphorylation

protein amino acid dephosphorylation

cell surface receptor linked signal transduction

T cell differentiation

B cell proliferation

positive regulation of T cell proliferation

positive regulation of protein kinase activity

T cell receptor signaling pathway

T cell receptor signaling pathway

B cell receptor signaling pathway

positive regulation of antigen receptor-mediated signaling pathway

release of sequestered calcium ion into cytosol

defense response to virus

regulation of cell cycle

integral to plasma membrane

focal adhesion

membrane

protein tyrosine phosphatase activity

protein tyrosine phosphatase activity

receptor activity

transmembrane receptor protein tyrosine phosphatase activity

hydrolase activity

phosphoric monoester hydrolase activity

protein kinase binding

protein kinase binding

Cell adhesion molecules (CAMs)

T cell receptor signaling pathway

1 40522_at GLUL glutamate-ammonia ligase (glutamine synthetase) 1 -180618291 X59834 1q31 Hs.518525 25

regulation of neurotransmitter levels

glutamine biosynthetic process

nitrogen compound metabolic process

cytoplasm

glutamate-ammonia ligase activity

ligase activity

Glutamate metabolism

Peptidoglycan biosynthesis

Nitrogen metabolism

1 40780_at CTBP2 C-terminal binding protein 2 10 -126666407 AF016507 10q26.13 Hs.501345 21

metabolic process

negative regulation of cell proliferation

viral genome replication

oxidoreductase activity

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

cofactor binding

NAD binding

Wnt signaling pathway

Notch signaling pathway

Chronic myeloid leukemia

1 40787_at WIPF2 WAS/WASL interacting protein family, member 2 17 35629099 U90911 17q21.2 Hs.421622 Hs.694045 11

cytoplasm

cytoskeleton

actin binding

 
1 40790_at BHLHB2 basic helix-loop-helix domain containing, class B, 2 3 4996207 AB004066 3p26 Hs.171825 21

negative regulation of transcription, DNA-dependent

nucleus

transcription factor activity

protein binding

transcription repressor activity

Circadian rhythm

1 40832_s_at TOR1AIP1 torsin A interacting protein 1 1 178118042 AL050126 1q24.2 Hs.496459 10

membrane

integral to membrane

 
1 41136_s_at APP amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) 21 -26174732 X13466 21q21.2 21q21.3 Hs.434980 561

cellular copper ion homeostasis

endocytosis

apoptosis

cell adhesion

Notch signaling pathway

neuromuscular process

extracellular region

integral to plasma membrane

cell surface

membrane

serine-type endopeptidase inhibitor activity

serine-type endopeptidase inhibitor activity

iron ion binding

copper ion binding

heparin binding

zinc ion binding

identical protein binding

metal ion binding

Neurodegenerative Disorders

Alzheimer's disease

1 41155_at CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 5 138117005 U03100 5q31 Hs.534797 44

cell adhesion

apical junction assembly

cytoplasm

actin cytoskeleton

cell junction

structural molecule activity

protein binding

vinculin binding

cadherin binding

Adherens junction

Tight junction

Leukocyte transendothelial migration

Endometrial cancer

1 41164_at IGHM immunoglobulin heavy constant mu 14   X67301 14q32.33 Hs.510635 24

activation of MAPK activity

immune response

biological_process

immunoglobulin mediated immune response

antigen processing and presentation

positive regulation of B cell proliferation

early endosome to late endosome transport

positive regulation of endocytosis

positive regulation of peptidyl-tyrosine phosphorylation

B cell receptor signaling pathway

membrane fraction

external side of plasma membrane

membrane

B cell receptor complex

immunoglobulin complex, circulating

perinuclear region of cytoplasm

antigen binding

antigen binding

receptor activity

transmembrane receptor activity

protein binding

 
1 41165_g_at IGHM immunoglobulin heavy constant mu 14   X67301 14q32.33 Hs.510635 24

activation of MAPK activity

immune response

biological_process

immunoglobulin mediated immune response

antigen processing and presentation

positive regulation of B cell proliferation

early endosome to late endosome transport

positive regulation of endocytosis

positive regulation of peptidyl-tyrosine phosphorylation

B cell receptor signaling pathway

membrane fraction

external side of plasma membrane

membrane

B cell receptor complex

immunoglobulin complex, circulating

perinuclear region of cytoplasm

antigen binding

antigen binding

receptor activity

transmembrane receptor activity

protein binding

 
1 41191_at PALLD palladin, cytoskeletal associated protein 4 169654791 AB023209 4q32.3 Hs.151220 18

protein amino acid phosphorylation

cytoskeleton organization and biogenesis

nucleus

actin filament

vascular endothelial growth factor receptor activity

protein binding

ATP binding

muscle alpha-actinin binding

 
1 41233_at DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 7 156822471, 156822470 AB014888 7q36.3 Hs.490745 21

protein folding

response to unfolded protein

negative regulation of caspase activity

intermediate filament organization

nucleus

cytoplasm

perinuclear region of cytoplasm

ATPase activator activity

heat shock protein binding

chaperone binding

 
1 41723_s_at HLA-DRB5 major histocompatibility complex, class II, DR beta 5 6 -32593138 M32578 6p21.3 Hs.534322 63

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

immune response

integral to plasma membrane

membrane

integral to membrane

MHC class II protein complex

MHC class II receptor activity

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Hematopoietic cell lineage

Type I diabetes mellitus

1 41764_at APOC1 apolipoprotein C-I 19 50109760 AA976838 19q13.2 Hs.110675 43

lipid metabolic process

lipid transport

lipoprotein metabolic process

extracellular region

endoplasmic reticulum

lipid transporter activity

 
1 32148_at FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 13 97593434 AI701049 13q32.2 Hs.403917 9

regulation of Rho protein signal transduction

intracellular

cytoplasm

cytoskeleton

extrinsic to membrane

guanyl-nucleotide exchange factor activity

Rho guanyl-nucleotide exchange factor activity

Rho guanyl-nucleotide exchange factor activity

binding

cytoskeletal protein binding

 
1 32190_at FADS2 fatty acid desaturase 2 11 61352288 AL050118 11q12-q13.1 Hs.502745 15

lipid metabolic process

fatty acid biosynthetic process

unsaturated fatty acid biosynthetic process

membrane fraction

integral to plasma membrane

membrane

iron ion binding

oxidoreductase activity

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

heme binding

Linoleic acid metabolism

PPAR signaling pathway

1 32251_at TCEAL4 transcription elongation factor A (SII)-like 4 X 102727074 AA149307 Xq22.2 Hs.194329 10

transcription

regulation of transcription, DNA-dependent

 
1 32773_at HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 6 32713160 AA868382 6p21.3 Hs.387679 89

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

immune response

immune response

antigen processing and presentation

integral to plasma membrane

membrane

integral to membrane

MHC class II protein complex

MHC class II receptor activity

MHC class II receptor activity

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Type I diabetes mellitus

1 32787_at ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 12 54760158 M34309 12q13 Hs.118681 85

protein amino acid phosphorylation

protein amino acid phosphorylation

signal transduction

transmembrane receptor protein tyrosine kinase signaling pathway

peripheral nervous system development

heart development

integral to plasma membrane

membrane

apical plasma membrane

lateral plasma membrane

nucleotide binding

transmembrane receptor protein tyrosine kinase activity

receptor activity

epidermal growth factor receptor activity

protein binding

ATP binding

transferase activity

protein heterodimerization activity

ErbB signaling pathway

Calcium signaling pathway

1 32794_g_at TRBC1 T cell receptor beta constant 1 7   X00437 7q34 Hs.654496 5

immune response

membrane

receptor activity

protein binding

 
1 32846_s_at KTN1 kinectin 1 (kinesin receptor) 14 55116677 D13629 14q22.1 Hs.509414 26

microtubule-based movement

membrane fraction

endoplasmic reticulum

endoplasmic reticulum membrane

integral to plasma membrane

membrane

molecular_function

receptor activity

 
1 33338_at STAT1 signal transducer and activator of transcription 1, 91kDa 2 -191548509, -191542121 M97936 2q32.2 Hs.694776 225

regulation of progression through cell cycle

transcription

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

caspase activation

signal transduction

intracellular signaling cascade

I-kappaB kinase/NF-kappaB cascade

tyrosine phosphorylation of STAT protein

STAT protein nuclear translocation

response to virus

nucleus

nucleus

cytoplasm

transcription factor activity

transcription factor activity

signal transducer activity

hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity

calcium ion binding

protein binding

Toll-like receptor signaling pathway

Jak-STAT signaling pathway

Pancreatic cancer

1 33355_at PBX1 pre-B-cell leukemia homeobox 1 1 162795560 AL049381 1q23 Hs.654412 41

regulation of transcription, DNA-dependent

transcription from RNA polymerase II promoter

C21-steroid hormone biosynthetic process

sex differentiation

embryonic development

cell differentiation

hindbrain development

regulation of transcriptional preinitiation complex assembly

nucleus

nucleus

transcription factor activity

transcription factor activity

protein binding

protein binding

sequence-specific DNA binding

 
1 33399_at C14orf147 chromosome 14 open reading frame 147 14 -33971895 AA142942 14q13.1 Hs.269909 3

membrane

integral to membrane

 
1 33439_at ZEB1 zinc finger E-box binding homeobox 1 10 31648147 D15050 10p11.2 Hs.124503 29

negative regulation of transcription from RNA polymerase II promoter

transcription

regulation of transcription, DNA-dependent

immune response

central nervous system development

cell proliferation

embryonic morphogenesis

intracellular

nucleus

nucleic acid binding

transcription factor activity

transcription factor activity

transcription coactivator activity

transcription corepressor activity

zinc ion binding

zinc ion binding

sequence-specific DNA binding

metal ion binding

 
1 33452_at PLAT plasminogen activator, tissue 8 -42151392 M15518 8p12 Hs.491582 141

protein modification process

proteolysis

proteolysis

blood coagulation

extracellular region

peptidase activity

plasminogen activator activity

Complement and coagulation cascades

1 33820_g_at HSPA8 heat shock 70kDa protein 8 11 -122433410 X13794 11q24.1 Hs.180414 96

protein folding

response to unfolded protein

intracellular

cytoplasm

cell surface

nucleotide binding

protein binding

ATP binding

ATPase activity, coupled

 
1 33821_at ELOVL5 ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) 6 -53240154 AL034374 6p21.1-p12.1 Hs.520189 10

fatty acid biosynthetic process

endoplasmic reticulum

membrane

integral to membrane

 
1 33845_at HNRPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 5 -178973785 W28483 5q35.3 Hs.604001 26

mRNA processing

RNA splicing

nucleus

spliceosome

heterogeneous nuclear ribonucleoprotein complex

nucleotide binding

nucleic acid binding

RNA binding

protein binding

poly(U) binding

 
1 33929_at GPC1 glypican 1 2 241023787 X54232 2q35-q37 Hs.328232 24

proteinaceous extracellular matrix

extracellular space

integral to plasma membrane

membrane

GPI anchor binding

 
1 33933_at WFDC2 WAP four-disulfide core domain 2 20 43531807 X63187 20q12-q13.2 Hs.2719 16

proteolysis

spermatogenesis

extracellular region

extracellular space

serine-type endopeptidase inhibitor activity

 
1 34307_at TM9SF2 transmembrane 9 superfamily member 2 13 98951728 U81006 13q32.3 Hs.654824 9

transport

endosome

integral to plasma membrane

membrane

 
1 34308_at HIST1H2AC histone cluster 1, H2ac 6 26232351 U90551 6p21.3 Hs.656746 19

nucleosome assembly

chromosome organization and biogenesis (sensu Eukaryota)

nucleosome

nucleus

chromosome

DNA binding

 
1 34342_s_at SPP1 secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) 4 89115825 AF052124 4q21-q25 Hs.313 162

ossification

cell adhesion

cell-matrix adhesion

negative regulation of bone mineralization

proteinaceous extracellular matrix

extracellular space

cytokine activity

integrin binding

protein binding

Cell Communication

Focal adhesion

ECM-receptor interaction

Toll-like receptor signaling pathway

1 34363_at SEPP1 selenoprotein P, plasma, 1 5 -42835739, -42835738 Z11793 5q31 Hs.275775 Hs.653366 22

selenium metabolic process

response to oxidative stress

brain development

locomotory behavior

post-embryonic development

sexual reproduction

growth

extracellular region

extracellular space

selenium binding

 
1 34385_at SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1 159550789 U57877 1q23.3 Hs.444472 15

tricarboxylic acid cycle

tricarboxylic acid cycle

electron transport

electron transport

transport

mitochondrion

membrane

integral to membrane

respiratory chain complex II

succinate dehydrogenase activity

iron ion binding

metal ion binding

Citrate cycle (TCA cycle)

Oxidative phosphorylation

1 34774_at PPT1 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) 1 -40310970 U44772 1p32 Hs.3873 34

protein depalmitoylation

protein depalmitoylation

DNA fragmentation during apoptosis

protein modification process

receptor-mediated endocytosis

pinocytosis

lysosomal lumen acidification

nervous system development

brain development

brain development

visual perception

protein transport

lipid catabolic process

sphingolipid catabolic process

protein catabolic process

negative regulation of cell growth

lipid raft organization and biogenesis

negative regulation of neuron apoptosis

positive regulation of receptor mediated endocytosis

positive regulation of pinocytosis

neuron development

regulation of synapse structure and activity

response to stimulus

cofactor transport

cofactor metabolic process

extracellular region

extracellular region

membrane fraction

nucleus

lysosome

lysosome

Golgi apparatus

cytosol

synaptic vesicle

axon

lipid raft

palmitoyl-(protein) hydrolase activity

palmitoyl-(protein) hydrolase activity

palmitoyl-(protein) hydrolase activity

palmitoyl-CoA hydrolase activity

palmitoyl-CoA hydrolase activity

hydrolase activity

Fatty acid elongation in mitochondria

1 34819_at CD164 CD164 molecule, sialomucin 6 -109794415 D14043 6q21 Hs.520313 12

immune response

cell adhesion

heterophilic cell adhesion

negative regulation of cell adhesion

signal transduction

multicellular organismal development

negative regulation of cell proliferation

negative regulation of cell proliferation

hemopoiesis

membrane fraction

soluble fraction

endosome

plasma membrane

integral to plasma membrane

integral to plasma membrane

 
1 34859_at MAGED2 melanoma antigen family D, 2 X 54852217, 54850895, 54851521 Z98046 Xp11.2 Hs.522665 11    
1 34860_g_at MAGED2 melanoma antigen family D, 2 X 54852217, 54850895, 54851521 Z98046 Xp11.2 Hs.522665 11    
1 35275_at CA12 carbonic anhydrase XII 15 -61402783 AL050025 15q22 Hs.210995 22

one-carbon compound metabolic process

membrane

integral to membrane

carbonate dehydratase activity

zinc ion binding

lyase activity

metal ion binding

Nitrogen metabolism

1 35371_at LRBA LPS-responsive vesicle trafficking, beach and anchor containing 4 -151405045 M83822 4q31.3 Hs.480938 8

biological_process

cellular_component

cytoplasmic membrane-bound vesicle

molecular_function

protein binding

 
1 35742_at C16orf45 chromosome 16 open reading frame 45 16 15435825 U95740 16p13.11 Hs.460095 4

protein binding

 
1 35747_at NPTN neuroplastin 15 -71639410 AF035287 15q22 Hs.187866 9

homophilic cell adhesion

positive regulation of long-term neuronal synaptic plasticity

integral to membrane

presynaptic membrane

cell adhesion molecule binding

 
1 35754_at TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 14 -74667923 L40391 14q24.3 Hs.74137 Hs.684601 18

ER to Golgi vesicle-mediated transport

protein transport

regulated secretory pathway

vesicle targeting, to, from or within Golgi

microsome

ER-Golgi intermediate compartment

cis-Golgi network

membrane

integral to membrane

zymogen granule membrane

protein binding

 
1 35766_at KRT18 keratin 18 12 51629109, 51628921 X12883 12q13 Hs.406013 81

cell cycle

anatomical structure morphogenesis

Golgi to plasma membrane CFTR protein transport

cytoplasm

keratin filament

structural constituent of cytoskeleton

protein binding

Cell Communication

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

1 35793_at G3BP2 GTPase activating protein (SH3 domain) binding protein 2 4 -76786990 AB014560 4q21.1 Hs.303676 13

transport

cytoplasmic sequestering of NF-kappaB

Ras protein signal transduction

mRNA transport

intracellular

cytoplasm

nucleotide binding

RNA binding

protein binding

receptor signaling complex scaffold activity

 
1 35807_at CYBA cytochrome b-245, alpha polypeptide 16 -87237198 M21186 16q24 Hs.513803 74

electron transport

superoxide metabolic process

transport

cytoplasm

mitochondrion

membrane

iron ion binding

protein binding

electron carrier activity

heme binding

metal ion binding

Leukocyte transendothelial migration

1 35844_at SDC4 syndecan 4 20 -43387344 D79206 20q12 Hs.632267 48

biological_process

integral to plasma membrane

cell surface

membrane

molecular_function

cytoskeletal protein binding

ECM-receptor interaction

Cell adhesion molecules (CAMs)

1 36110_at RAB5A RAB5A, member RAS oncogene family 3 19963762 M28215 3p24-p22 Hs.475663 52

endocytosis

small GTPase mediated signal transduction

protein transport

ruffle

early endosome

plasma membrane

endocytic vesicle

lipid raft

nucleotide binding

GTPase activity

protein binding

protein binding

GTP binding

Amyotrophic lateral sclerosis (ALS)

1 36133_at DSP desmoplakin 6 7486868 AL031058 6p24 Hs.519873 52

epidermis development

peptide cross-linking

keratinocyte differentiation

cornified envelope

cytoplasm

intermediate filament

cell-cell adherens junction

structural constituent of cytoskeleton

protein binding, bridging

 
1 36155_at SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 10 -73488798 D87465 10pter-q25.3 Hs.523009 9

synaptogenesis

extracellular matrix organization and biogenesis

regulation of cell differentiation

proteinaceous extracellular matrix

calcium ion binding

 
1 36161_at AP2B1 adaptor-related protein complex 2, beta 1 subunit 17 30938394 M34175 17q11.2-q12 Hs.514819 28

protein complex assembly

intracellular protein transport

vesicle-mediated transport

membrane

membrane coat

clathrin adaptor complex

protein binding

protein binding

protein transporter activity

 
1 36165_at COX6C cytochrome c oxidase subunit VIc 8 -100959547 W51774 8q22-q23 Hs.351875 8

electron transport

mitochondrion

membrane

integral to membrane

cytochrome-c oxidase activity

oxidoreductase activity

Oxidative phosphorylation

1 36171_at SUB1 SUB1 homolog (S. cerevisiae) 5 32621433 AI521453 5p13.3 Hs.229641 28

transcription

regulation of transcription from RNA polymerase II promoter

transcription factor complex

DNA binding

single-stranded DNA binding

transcription coactivator activity

protein binding

 
1 36198_at TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1 -233339282 D13641 1q42 Hs.533192 22

protein targeting to mitochondrion

protein import into mitochondrion

mitochondrion

mitochondrial outer membrane translocase complex

membrane

integral to membrane

outer membrane

protein transmembrane transporter activity

unfolded protein binding

 
1 36591_at TUBA4A tubulin, alpha 4a 2 -219823244 X06956 2q35 Hs.75318 66

microtubule-based movement

protein polymerization

microtubule

protein complex

nucleotide binding

GTPase activity

structural molecule activity

protein binding

GTP binding

Gap junction

Pathogenic Escherichia coli infection - EHEC

Pathogenic Escherichia coli infection - EPEC

1 36627_at SPARCL1 SPARC-like 1 (mast9, hevin) 4 -88613511 X86693 4q22.1 Hs.62886 11

proteinaceous extracellular matrix

calcium ion binding

 
1 36628_at RALBP1 ralA binding protein 1 18 9465529 L42542 18p11.3 Hs.528993 30

transport

chemotaxis

signal transduction

signal transduction

small GTPase mediated signal transduction

regulation of GTPase activity

positive regulation of Cdc42 GTPase activity

intracellular

membrane

GTPase activator activity

protein binding

ATPase activity

Ral GTPase binding

Rac GTPase activator activity

ATPase activity, coupled to movement of substances

Rac GTPase binding

Pancreatic cancer

1 36634_at BTG2 BTG family, member 2 1 201541286 U72649 1q32 Hs.519162 36

DNA repair

transcription

regulation of transcription, DNA-dependent

protein amino acid methylation

negative regulation of cell proliferation

anterior/posterior pattern formation

transcription factor activity

protein binding

 
1 36636_at OAT ornithine aminotransferase (gyrate atrophy) 10 -126075861 M12267 10q26 Hs.523332 28

amino acid metabolic process

ornithine metabolic process

visual perception

mitochondrion

mitochondrial matrix

ornithine-oxo-acid transaminase activity

protein binding

transferase activity

pyridoxal phosphate binding

Arginine and proline metabolism

1 36638_at CTGF connective tissue growth factor 6 -132311011 X78947 6q23.1 Hs.591346 116

cartilage condensation

ossification

angiogenesis

regulation of cell growth

DNA replication

cell adhesion

cell-matrix adhesion

integrin-mediated signaling pathway

fibroblast growth factor receptor signaling pathway

epidermis development

response to wounding

cell migration

cell differentiation

extracellular region

proteinaceous extracellular matrix

extracellular space

soluble fraction

plasma membrane

integrin binding

protein binding

insulin-like growth factor binding

heparin binding

 
1 36647_at IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1 218334077 AA526812 1q41 Hs.262823 5

isoleucyl-tRNA aminoacylation

cytoplasm

mitochondrion

nucleotide binding

isoleucine-tRNA ligase activity

ATP binding

zinc ion binding

ligase activity

Valine, leucine and isoleucine biosynthesis

Aminoacyl-tRNA biosynthesis

1 36658_at DHCR24 24-dehydrocholesterol reductase 1 -55087887 D13643 1p33-p31.1 Hs.498727 14

electron transport

cholesterol biosynthetic process

cholesterol biosynthetic process

apoptosis

anti-apoptosis

response to oxidative stress

cell cycle arrest

protein localization

tissue development

membrane organization and biogenesis

male genitalia development

plasminogen activation

amyloid precursor protein catabolic process

negative regulation of caspase activity

neuroprotection

skin development

nucleus

endoplasmic reticulum

endoplasmic reticulum membrane

membrane

integral to membrane

oxidoreductase activity

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

enzyme binding

peptide antigen binding

Biosynthesis of steroids

1 36938_at ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 8 -17958213 U70063 8p22-p21.3 Hs.527412 22

fatty acid metabolic process

ceramide metabolic process

carboxylic acid metabolic process

lysosome

hydrolase activity

ceramidase activity

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Sphingolipid metabolism

1 36946_at DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 21 37714470, 37714471, 37713076, 37661728 D86550 21q22.13 Hs.368240 40

nervous system development

peptidyl-tyrosine phosphorylation

protein amino acid autophosphorylation

nucleus

nuclear speck

nucleotide binding

protein serine/threonine kinase activity

non-membrane spanning protein tyrosine kinase activity

ATP binding

kinase activity

transferase activity

protein self-association

 
1 36975_at TMEM66 transmembrane protein 66 8 -30040173 W26659 8p12 Hs.521487 9

membrane

integral to membrane

 
1 36981_at SRP9 signal recognition particle 9kDa 1 224032153 AF070649 1q42.12 Hs.511425 Hs.642815 9

SRP-dependent cotranslational protein targeting to membrane

negative regulation of translational elongation

cytoplasm

signal recognition particle receptor complex

signal recognition particle, endoplasmic reticulum targeting

signal recognition particle

signal recognition particle binding

protein binding

7S RNA binding

Protein export

1 37000_at BRP44 brain protein 44 1 -166153933 AL035304 1q24 Hs.517768 9

mitochondrion

 
1 37023_at LCP1 lymphocyte cytosolic protein 1 (L-plastin) 13 -45598059 J02923 13q14.3 Hs.381099 33

biological_process

actin filament bundle formation

ruffle

phagocytic cup

cytoplasm

cytosol

actin filament

actin binding

calcium ion binding

calcium ion binding

identical protein binding

actin filament binding

 
1 37035_at SERP1 stress-associated endoplasmic reticulum protein 1 3 -151742470 AI557272 3q25.1 Hs.518326 10

protein amino acid glycosylation

protein targeting

response to stress

plasma membrane organization and biogenesis

protein transport

endoplasmic reticulum

ribosome

membrane

integral to membrane

 
1 37038_at ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1 94656598 X83467 1p22-p21 Hs.76781 21

transport

peroxisome organization and biogenesis

peroxisomal long-chain fatty acid import

mitochondrion

mitochondrial inner membrane

peroxisome

peroxisomal membrane

integral to peroxisomal membrane

membrane

integral to membrane

nucleotide binding

protein binding

ATP binding

ATPase activity

ATPase activity, coupled to transmembrane movement of substances

ABC transporters - General

1 37292_at MAML1 mastermind-like 1 (Drosophila) 5 179092456 D83785 5q35 Hs.631951 13

transcription

regulation of transcription, DNA-dependent

Notch signaling pathway

positive regulation of transcription from RNA polymerase II promoter

nucleus

transcription coactivator activity

Notch signaling pathway

1 37304_at CBX1 chromobox homolog 1 (HP1 beta homolog Drosophila ) 17 -43502421 U35451 17q Hs.77254 35

chromatin assembly or disassembly

chromatin

female pronucleus

male pronucleus

nucleus

nucleoplasm

polytene chromosome chromocenter

nuclear heterochromatin

centric heterochromatin

chromatin binding

identical protein binding

 
1 37332_r_at ALDH4A1 aldehyde dehydrogenase 4 family, member A1 1 -19070512 U24267 1p36 Hs.77448 12

proline biosynthetic process

proline catabolic process

metabolic process

mitochondrion

mitochondrial matrix

1-pyrroline-5-carboxylate dehydrogenase activity

aldehyde dehydrogenase (NAD) activity

electron carrier activity

oxidoreductase activity

Glutamate metabolism

Arginine and proline metabolism

1 37344_at HLA-DMA major histocompatibility complex, class II, DM alpha 6 -33024373, -4297248, -4102468 X62744 6p21.3 Hs.351279 40

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

immune response

biological_process

antigen processing and presentation

cellular_component

lysosome

endosome

membrane

integral to membrane

MHC class II protein complex

protein binding

MHC class II receptor activity

Cell adhesion molecules (CAMs)

Antigen processing and presentation

Type I diabetes mellitus

1 37393_at HES1 hairy and enhancer of split 1, (Drosophila) 3 195336627 L19314 3q28-q29 Hs.250666 27

negative regulation of transcription from RNA polymerase II promoter

regulation of transcription, DNA-dependent

cell adhesion

nervous system development

positive regulation of cell proliferation

lung development

auditory receptor cell differentiation

auditory receptor cell fate determination

cell fate commitment

negative regulation of auditory receptor cell differentiation

negative regulation of neuron differentiation

cell maturation

nucleus

cytoplasm

DNA binding

transcription repressor activity

Notch signaling pathway

Maturity onset diabetes of the young

1 37405_at SELENBP1 selenium binding protein 1 1 -149603404 U29091 1q21-q22 Hs.632460 13

protein transport

cytoplasm

membrane

selenium binding

selenium binding

 
1 37732_at RYBP RING1 and YY1 binding protein 3 -72506440 AL049940